Institute for Social Medicine and Family Medicine, School of Medicine, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
School of Public Health, The University of Hong Kong, 7 Sassoon Road, Pokfulam 10000, Hong Kong.
Int J Environ Res Public Health. 2019 Jan 25;16(3):335. doi: 10.3390/ijerph16030335.
Massive misuse of antibiotics is one of the most important reasons for antimicrobial resistance (AMR). Misconceptions of antibiotics contribute to antibiotic misuse behaviors. This study aims to examine whether university students hold the misconception that (literally means anti-inflammatory drug in Chinese), and association between this misconception and antibiotic misuse behaviors. A cross-sectional study was conducted among university students using the cluster random sampling method in six universities of six regions in China (one university per region). The Chi-square test was used to assess the relationship between the misconception and antibiotic misuse behaviors. Logistic regression was conducted to identify the risk factors for antibiotic misuse behaviors. 11,192 of university students completed the entire questionnaire. There were 3882 (34.7%) students who were considered to have the misconception. Female students were more likely to have the misconception compared with males (36.7% vs. 32.6%, P < 0.001). Those students with a background of social science/humanities were more likely to have the misconception compared with those from science and medicine (44.1% vs. 30.3% vs. 20.1%, P < 0.001). Students came from rural areas compared with those from urban areas (37.5% vs. 32.5%, P < 0.001) were more likely to have the misconception. Students who had the misconception were 1.51 (95% CI 1.21⁻1.89, P < 0.001) times, 1.34 (95% CI 1.21⁻1.48, P < 0.001) times, and 1.36 (95% CI 1.24⁻1.50, P < 0.001) times more likely to report self-medication, request to obtain antibiotics, and take antibiotics prophylactically than those who did not have this misconception, respectively. The high proportion of university students' misconception on is worth more attention. Effective health education and interventions need to be promoted among university students and the whole population.
大量滥用抗生素是导致抗菌药物耐药性(AMR)的最重要原因之一。对抗生素的误解导致了抗生素的滥用行为。本研究旨在检验大学生是否存在对 (中文字面意思为抗炎药)的误解,并探讨这种误解与抗生素滥用行为之间的关系。采用整群随机抽样方法,在中国六个地区的六所大学(每个地区一所大学)进行了一项大学生横断面研究。采用卡方检验评估误解与抗生素滥用行为之间的关系。采用 logistic 回归分析确定抗生素滥用行为的危险因素。共有 11192 名大学生完成了整个问卷。有 3882 名(34.7%)学生被认为存在这种误解。与男性相比,女性更有可能存在这种误解(36.7%比 32.6%,P < 0.001)。与来自科学和医学背景的学生相比,来自社会科学/人文背景的学生更有可能存在这种误解(44.1%比 30.3%比 20.1%,P < 0.001)。与来自城市地区的学生相比,来自农村地区的学生更有可能存在这种误解(37.5%比 32.5%,P < 0.001)。存在这种误解的学生自述自行用药、要求获取抗生素和预防性使用抗生素的可能性分别是没有这种误解的学生的 1.51 倍(95%CI 1.21⁻1.89,P < 0.001)、1.34 倍(95%CI 1.21⁻1.48,P < 0.001)和 1.36 倍(95%CI 1.24⁻1.50,P < 0.001)。大学生对抗生素的这种误解比例较高,值得引起更多关注。需要在大学生和整个人群中推广有效的健康教育和干预措施。