Rubin Courtney B, Rosenbach Misha
Department of Dermatology, University of Pennsylvania, Philadelphia, USA.
Cutis. 2019 Feb;103(2):102-106.
Although granuloma annulare (GA) is a relatively common dermatologic condition, little is known about its epidemiology and pathogenesis. Additionally, there is conflicting evidence regarding its association with other diseases. In our retrospective study, we attempted to determine the number of cases of GA seen annually at a large academic center and clarify disease associations with GA. We utilized PennSeek, a tool developed by the Penn Medicine Data Analytics Center to search electronic medical records (EMRs), to identify all cases of GA seen at the University of Pennsylvania (Philadelphia, Pennsylvania) from 2008 to 2014. All biopsy-proven cases of GA from 2010 to 2014 were reviewed for medical comorbidities, medications, treatments, and outcomes. On average, the percentage of patients given a diagnosis of GA annually was 0.22%. There were 133 cases of biopsy-proven GA that were reviewed. The findings solidify our understanding of the epidemiology of GA and diseases that can be associated with GA.
尽管环状肉芽肿(GA)是一种相对常见的皮肤病,但对其流行病学和发病机制知之甚少。此外,关于它与其他疾病的关联存在相互矛盾的证据。在我们的回顾性研究中,我们试图确定一家大型学术中心每年所见的GA病例数,并阐明与GA相关的疾病关联。我们利用宾夕法尼亚大学医学数据分析中心开发的工具PennSeek来搜索电子病历(EMR),以识别2008年至2014年在宾夕法尼亚大学(宾夕法尼亚州费城)所见的所有GA病例。对2010年至2014年所有经活检证实的GA病例进行了医学合并症、药物、治疗和结局的审查。平均而言,每年被诊断为GA的患者比例为0.22%。共审查了133例经活检证实的GA病例。这些发现巩固了我们对GA流行病学以及可能与GA相关疾病的理解。