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老年人糖尿病治疗:内分泌学会*临床实践指南。

Treatment of Diabetes in Older Adults: An Endocrine Society* Clinical Practice Guideline.

机构信息

Icahn School of Medicine at Mount Sinai, New York, New York.

University Medical Center Utrecht, Utrecht, Netherlands.

出版信息

J Clin Endocrinol Metab. 2019 May 1;104(5):1520-1574. doi: 10.1210/jc.2019-00198.

Abstract

OBJECTIVE

The objective is to formulate clinical practice guidelines for the treatment of diabetes in older adults.

CONCLUSIONS

Diabetes, particularly type 2, is becoming more prevalent in the general population, especially in individuals over the age of 65 years. The underlying pathophysiology of the disease in these patients is exacerbated by the direct effects of aging on metabolic regulation. Similarly, aging effects interact with diabetes to accelerate the progression of many common diabetes complications. Each section in this guideline covers all aspects of the etiology and available evidence, primarily from controlled trials, on therapeutic options and outcomes in this population. The goal is to give guidance to practicing health care providers that will benefit patients with diabetes (both type 1 and type 2), paying particular attention to avoiding unnecessary and/or harmful adverse effects.

摘要

目的

制定治疗老年糖尿病患者的临床实践指南。

结论

糖尿病,特别是 2 型糖尿病,在普通人群中越来越普遍,尤其是在 65 岁以上的人群中。在这些患者中,疾病的潜在病理生理学受到衰老对代谢调节的直接影响的加剧。同样,衰老的影响与糖尿病相互作用,加速了许多常见糖尿病并发症的进展。本指南的每一节都涵盖了该人群中治疗选择和结果的病因学和现有证据的各个方面,主要来自对照试验。目的是为执业医疗保健提供者提供指导,使糖尿病(1 型和 2 型)患者受益,特别注意避免不必要和/或有害的不良反应。

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