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实施 1-3 级腰椎融合手术后加速康复外科方案后,住院时间、麻醉药物使用和疼痛减少。

Reductions in length of stay, narcotics use, and pain following implementation of an enhanced recovery after surgery program for 1- to 3-level lumbar fusion surgery.

机构信息

Departments of1Neurological Surgery and.

2Anesthesiology, University of Miami Miller School of Medicine, Miami, Florida.

出版信息

Neurosurg Focus. 2019 Apr 1;46(4):E4. doi: 10.3171/2019.1.FOCUS18692.

Abstract

OBJECTIVELumbar fusion is typically associated with high degrees of pain and immobility. The implementation of an enhanced recovery after surgery (ERAS) approach has been successful in speeding the recovery after other surgical procedures. In this paper, the authors examined the results of early implementation of ERAS for lumbar fusion.METHODSBeginning in March 2018 at the authors' institution, all patients undergoing posterior, 1- to 3-level lumbar fusion surgery by any of 3 spine surgeons received an intraoperative injection of liposomal bupivacaine, immediate single postoperative infusion of 1-g intravenous acetaminophen, and daily postoperative visits from the authors' multidisciplinary ERAS care team. Non-English- or non-Spanish-speaking patients and those undergoing nonelective or staged procedures were excluded. Reviews of medical records were conducted for the ERAS cohort of 57 patients and a comparison group of 40 patients who underwent the same procedures during the 6 months before implementation.RESULTSGroups did not differ significantly with regard to sex, age, or BMI (all p > 0.05). Length of stay was significantly shorter in the ERAS cohort than in the control cohort (2.9 days vs 3.8 days; p = 0.01). Patients in the ERAS group consumed significantly less oxycodone-acetaminophen than the controls on postoperative day (POD) 0 (408.0 mg vs 1094.7 mg; p = 0.0004), POD 1 (1320.0 mg vs 1708.4 mg; p = 0.04), and POD 3 (1500.1 mg vs 2105.4 mg; p = 0.03). Postoperative pain scores recorded by the physical therapy and occupational therapy teams and nursing staff each day were lower in the ERAS cohort than in controls, with POD 1 achieving significance (4.2 vs 6.0; p = 0.006). The total amount of meperidine (8.8 mg vs 44.7 mg; p = 0.003) consumed was also significantly decreased in the ERAS group, as was ondansetron (2.8 mg vs 6.0 mg; p = 0.02). Distance ambulated on each POD was farther in the ERAS cohort, with ambulation on POD 1 (109.4 ft vs 41.4 ft; p = 0.002) achieving significance.CONCLUSIONSIn this very initial implementation of the first phase of an ERAS program for short-segment lumbar fusion, the authors were able to demonstrate substantial positive effects on the early recovery process. Importantly, these effects were not surgeon-specific and could be generalized across surgeons with disparate technical predilections. The authors plan additional iterations to their ERAS protocols for continued quality improvements.

摘要

目的

腰椎融合术通常与高度疼痛和活动受限相关。术后加速康复(ERAS)方案在加速其他外科手术后的恢复方面取得了成功。本文作者研究了早期实施腰椎融合术 ERAS 的结果。

方法

自 2018 年 3 月起,作者所在机构的所有由 3 位脊柱外科医生实施的后路、1-3 级腰椎融合术患者在术中接受脂质体布比卡因注射,术后即刻单次静脉注射 1g 乙酰氨基酚,术后每天由作者所在的多学科 ERAS 护理团队进行随访。排除非英语或西班牙语患者以及非择期或分期手术患者。对 57 例 ERAS 队列患者和实施相同手术的 40 例对照组患者的病历进行回顾性分析。

结果

两组患者在性别、年龄或 BMI 方面无显著差异(均 p>0.05)。ERAS 组的住院时间明显短于对照组(2.9 天 vs 3.8 天;p=0.01)。ERAS 组患者在术后第 0 天(408.0mg 比 1094.7mg;p=0.0004)、第 1 天(1320.0mg 比 1708.4mg;p=0.04)和第 3 天(1500.1mg 比 2105.4mg;p=0.03)的曲马多-对乙酰氨基酚消耗量明显少于对照组。物理治疗和职业治疗团队以及护理人员每天记录的术后疼痛评分在 ERAS 组均低于对照组,第 1 天达到显著水平(4.2 比 6.0;p=0.006)。在 ERAS 组中,哌替啶(8.8mg 比 44.7mg;p=0.003)和昂丹司琼(2.8mg 比 6.0mg;p=0.02)的总消耗量也显著减少。ERAS 组在每个术后第 1 天的步行距离更远,术后第 1 天的步行距离(109.4 英尺比 41.4 英尺;p=0.002)达到显著水平。

结论

在对短节段腰椎融合术实施 ERAS 方案的第一阶段的初步实施中,作者能够证明对早期康复过程产生了显著的积极影响。重要的是,这些影响不是特定于外科医生的,并且可以在具有不同技术倾向的外科医生中推广。作者计划对 ERAS 方案进行进一步迭代,以持续提高质量。

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