细胞培养基配方及其在癌症代谢中的意义。
Cell Culture Medium Formulation and Its Implications in Cancer Metabolism.
作者信息
Ackermann Tobias, Tardito Saverio
机构信息
Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.
Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.
出版信息
Trends Cancer. 2019 Jun;5(6):329-332. doi: 10.1016/j.trecan.2019.05.004. Epub 2019 May 29.
Abstract
Historic cell culture media were designed to ensure continuous cancer cell proliferation in vitro. However, their composition does not recapitulate the nutritional environment of the tumor. Recent studies show that novel media formulations alleviate the nonphysiological constraints imposed by historic media, and lead to cell culture results that are more relevant to tumor metabolism.
摘要
传统的细胞培养基旨在确保癌细胞在体外持续增殖。然而，其成分并未重现肿瘤的营养环境。最近的研究表明，新型培养基配方减轻了传统培养基所带来的非生理限制，并产生了与肿瘤代谢更相关的细胞培养结果。
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