印度全球抗菌药物耐药性监测系统（GLASS）重点病原体的抗菌药物敏感性概况和耐药机制。
Antimicrobial susceptibility profile & resistance mechanisms of Global Antimicrobial Resistance Surveillance System (GLASS) priority pathogens from India.
机构信息
Department of Clinical Microbiology, Christian Medical College, Vellore, India.
Division of Epidemiology & Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
出版信息
Indian J Med Res. 2019 Feb;149(2):87-96. doi: 10.4103/ijmr.IJMR_214_18.
Abstract
Antimicrobial resistance is a major concern globally. Infections due to drug-resistant pathogens are becoming difficult and a challenge to treat. As treatment choices are limited due to the high-drug resistance rates, there is an increase in the health care cost, duration of hospital stay, morbidity and mortality rates. Understanding the true burden of antimicrobial resistance for a geographical location is important to guide effective empirical therapy. To have a national data, it is imperative to have a systemic data capturing across the country through surveillance studies. Very few surveillance studies have been conducted in India to generate national data on antimicrobial resistance. This review aims to report the cumulative antibiogram and the resistance mechanisms of Global Antimicrobial Resistance Surveillance System (GLASS) priority pathogens from India.
摘要
抗菌药物耐药性是一个全球性的主要关注点。由于耐药病原体引起的感染变得难以治疗，这是一个挑战。由于高耐药率导致治疗选择有限，因此医疗保健成本、住院时间、发病率和死亡率都有所增加。了解特定地理位置的抗菌药物耐药性的真实负担对于指导有效的经验性治疗非常重要。为了获得国家数据，必须通过监测研究在全国范围内进行系统的数据收集。印度开展的监测研究很少，无法生成关于抗菌药物耐药性的国家数据。本综述旨在报告来自印度的全球抗菌药物耐药性监测系统 (GLASS) 优先病原体的累积药敏谱和耐药机制。
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