Division of Dermatology, Department of Internal Medicine, University of Texas at Austin, Dell Medical School, 1601 Trinity Street, Building B, Stop Z0900, Austin, TX 78712, USA.
Division of Dermatology, Department of Internal Medicine, University of Texas at Austin, Dell Medical School, 1601 Trinity Street, Building B, Stop Z0900, Austin, TX 78712, USA.
Dermatol Clin. 2019 Oct;37(4):425-433. doi: 10.1016/j.det.2019.05.002. Epub 2019 Jul 10.
Nonmelanoma skin cancer (NMSC) is the most commonly diagnosed malignancy in the United States. Surgery is considered the gold standard treatment. Techniques include curettage and electrodesiccation, surgical excision, and Mohs micrographic surgery. While each is effective, there are relative advantages and disadvantages with respect to cost, time, quality of life, and role in patients with limited life expectancy. Preventing local tumor recurrence is the primary objective; however, recurrence rates are based on retrospective data, and high-quality comparator studies assessing effectiveness are scarce. Prospective and randomized controlled trials are imperative to create comprehensive, evidence-based recommendations for the surgical management of NMSC.
非黑素瘤皮肤癌(NMSC)是美国最常见的恶性肿瘤。手术被认为是金标准治疗。技术包括刮除术和电干燥术、手术切除和 Mohs 显微外科手术。虽然每种方法都有效,但在成本、时间、生活质量以及在预期寿命有限的患者中的作用方面,它们都有各自的优缺点。预防局部肿瘤复发是主要目标;然而,复发率是基于回顾性数据的,并且缺乏评估有效性的高质量对照研究。前瞻性和随机对照试验对于制定 NMSC 手术管理的综合、基于证据的建议至关重要。