一种用于活细胞中 Cu 检测和生物成像的新型胆固醇偶联荧光探针。
A novel cholesterol conjugated fluorescence probe for Cu detection and bioimaging in living cells.
机构信息
College of Chemistry and Materials Science, Fujian Normal University, Fuzhou, 350007, China.
College of Chemistry and Materials Science, Fujian Normal University, Fuzhou, 350007, China; Fujian Provincial University Engineering Research Center of Industrial Biocatalysis, Fujian Normal University, Fuzhou, 350117, China.
出版信息
Spectrochim Acta A Mol Biomol Spectrosc. 2020 Feb 15;227:117530. doi: 10.1016/j.saa.2019.117530. Epub 2019 Sep 13.
A cholesterol conjugated fluorescence probe T was designed and synthesized. The probe T can be used for recognition of Cu by the absorption spectrum, fluorescence spectrum, and naked eyes respectively in aqueous solution. The cell imaging experiments showed that the probe has good membrane permeability and a huge potentiality for the detection of Cu in living cells.
设计合成了一种胆固醇偶联的荧光探针 T。该探针 T 可分别通过吸收光谱、荧光光谱和肉眼在水溶液中识别 Cu。细胞成像实验表明，该探针具有良好的膜透过性，在活细胞中检测 Cu 具有巨大的应用潜力。
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