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建模英格兰与医疗保健相关感染有关的 NHS 年度成本和结果。

Modelling the annual NHS costs and outcomes attributable to healthcare-associated infections in England.

机构信息

Catalyst Consultants, Rickmansworth, UK

King's College London, London, UK.

出版信息

BMJ Open. 2020 Jan 22;10(1):e033367. doi: 10.1136/bmjopen-2019-033367.

Abstract

OBJECTIVES

To estimate the annual health economic impact of healthcare-associated infections (HCAIs) to the National Health Service (NHS) in England.

DESIGN

A modelling study based on a combination of published data and clinical practice.

SETTING

NHS hospitals in England.

PRIMARY AND SECONDARY OUTCOME MEASURES

Annual number of HCAIs, additional NHS cost, number of occupied hospital bed days and number of days front-line healthcare professionals (HCPs) are absent from work.

RESULTS

In 2016/2017, there were an estimated 653 000 HCAIs among the 13.8 million adult inpatients in NHS general and teaching hospitals in England, of which 22 800 patients died as a result of their infection. Additionally, there were an estimated 13 900 HCAIs among 810 000 front-line HCPs in the year. These infections were estimated to account for a total of 5.6 million occupied hospital bed days and 62 500 days of absenteeism among front-line HCPs. In 2016/2017, HCAIs were estimated to have cost the NHS an estimated £2.1 billion, of which 99.8% was attributable to patient management and 0.2% was the additional cost of replacing absent front-line HCPs with bank or agency staff for a period of time. When the framework of the model was expanded to include all NHS hospitals in England (by adding specialist hospitals), there were an estimated 834 000 HCAIs in 2016/2017 costing the NHS £2.7 billion, and accounting for 28 500 patient deaths, 7.1 million occupied hospital bed days (equivalent to 21% of the annual number of all bed days across all NHS hospitals in England) and 79 700 days of absenteeism among front-line HCPs.

CONCLUSION

This study should provide updated estimates with which to inform policy and budgetary decisions pertaining to preventing and managing these infections. Clinical and economic benefits could accrue from an increased awareness of the impact that HCAIs impose on patients, the NHS and society as a whole.

摘要

目的

估算与英格兰国民保健服务(NHS)相关的医疗保健相关感染(HCAI)对 NHS 的年度健康经济影响。

设计

基于已发表数据和临床实践的组合的建模研究。

设置

英格兰 NHS 医院。

主要和次要结果测量

HCAI 的年发生数、NHS 额外成本、占用医院病床日数和一线卫生保健专业人员(HCP)缺勤天数。

结果

在 2016/2017 年,英格兰 NHS 综合和教学医院的 1380 万成年住院患者中估计有 65.3 万例 HCAI,其中 2.2 万名患者因感染而死亡。此外,当年还估计有 8.1 万名一线 HCP 中有 1.39 万名发生 HCAI。这些感染估计共导致 560 万占用医院病床日和 6.25 万名一线 HCP 缺勤。2016/2017 年,HCAI 估计使 NHS 花费约 21 亿英镑,其中 99.8%归因于患者管理,0.2%是因在一段时间内用银行或代理人员替代缺勤的一线 HCP 而产生的额外成本。当将模型框架扩展到包括英格兰所有 NHS 医院(通过增加专科医院)时,2016/2017 年估计有 83.4 万例 HCAI,使 NHS 花费 27 亿英镑,并导致 2.8 万名患者死亡、710 万占用医院病床日(相当于英格兰所有 NHS 医院年度病床日数的 21%)和 7.97 万名一线 HCP 缺勤。

结论

本研究应提供更新的估计值,以便为预防和管理这些感染的政策和预算决策提供信息。提高对 HCAI 给患者、NHS 和整个社会带来的影响的认识,可能会带来临床和经济效益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/197b/7045184/d2ec6d0aa3f6/bmjopen-2019-033367f01.jpg

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