追踪全球威胁：耳念珠菌新型基因分型方法。
Tracking a Global Threat: a New Genotyping Method for Candida auris.
机构信息
Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Institut Pasteur, Molecular Mycology Unit, CNRS UMR2000, National Reference Center for Invasive Mycoses and Antifungals (NRCMA), Paris, France.
出版信息
mBio. 2020 Mar 10;11(2):e00259-20. doi: 10.1128/mBio.00259-20.
Abstract
Over the past decade, has emerged as an urgent threat to public health. Initially reported from cases of ear infections in Japan and Korea, has since been detected around the world. While whole-genome sequencing has been extensively used to trace the genetic relationships of the global emergence and local outbreaks, a recent report in describes a targeted genotyping method as a rapid and inexpensive method for classifying isolates (T. de Groot, Y. Puts, I. Berrio, A. Chowdhary, and J. F. Meis, mBio 11:e02971-19, https://doi.org/10.1128/mBio.02971-19, 2020).
摘要
在过去的十年中，已经成为公共卫生的紧迫威胁。该疾病最初是在日本和韩国的耳部感染病例中报告的，此后已在世界各地检测到。虽然全基因组测序已被广泛用于追踪全球出现和局部爆发的遗传关系，但最近在 mBio 上的一篇报告描述了一种靶向基因分型方法，该方法是一种快速且廉价的方法，可用于对分离株进行分类（T. de Groot、Y. Puts、I. Berrio、A. Chowdhary 和 J. F. Meis，mBio 11:e02971-19，https://doi.org/10.1128/mBio.02971-19，2020）。
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