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常见运动医学手术后的阿片类药物使用:系统评价。

Opioid Use After Common Sports Medicine Procedures: A Systematic Review.

机构信息

Department of Orthopaedic Surgery, Northwestern University, Chicago, Illinois.

出版信息

Sports Health. 2020 May-Jun;12(3):225-233. doi: 10.1177/1941738120913293. Epub 2020 Apr 9.

Abstract

CONTEXT

The prescription of opioids after elective surgical procedures has been a contributing factor to the current opioid epidemic in North America.

OBJECTIVE

To examine the opioid prescribing practices and rates of opioid consumption among patients undergoing common sports medicine procedures.

DATA SOURCES

A systematic review of the electronic databases EMBASE, MEDLINE, and PubMed was performed from database inception to December 2018.

STUDY SELECTION

Two investigators independently identified all studies reporting on postoperative opioid prescribing practices and consumption after arthroscopic shoulder, knee, or hip surgery. A total of 119 studies were reviewed, with 8 meeting eligibility criteria.

STUDY DESIGN

Systematic review.

LEVEL OF EVIDENCE

Level 4.

DATA EXTRACTION

The quantity of opioids prescribed and used were converted to milligram morphine equivalents (MMEs) for standardized reporting. The quality of each eligible study was evaluated using the Methodological Index for Non-Randomized Studies.

RESULTS

A total of 8 studies including 816 patients with a mean age of 43.8 years were eligible for inclusion. A mean of 610, 197, and 613 MMEs were prescribed to patients after arthroscopic procedures of the shoulder, knee, and hip, respectively. At final follow-up, 31%, 34%, and 64% of the prescribed opioids provided after shoulder, knee, and hip arthroscopy, respectively, still remained. The majority of patients (64%) were unaware of the appropriate disposal methods for surplus medication. Patients undergoing arthroscopic rotator cuff repair had the highest opioid consumption (471 MMEs), with 1 in 4 patients receiving a refill.

CONCLUSION

Opioids are being overprescribed for arthroscopic procedures of the shoulder, knee, and hip, with more than one-third of prescribed opioids remaining postoperatively. The majority of patients are unaware of the appropriate disposal techniques for surplus opioids. Appropriate risk stratification tools and evidence-based recommendations regarding pain management strategies after arthroscopic procedures are needed to help curb the growing opioid crisis.

摘要

背景

在北美,择期手术术后开具阿片类药物处方是目前阿片类药物流行的一个促成因素。

目的

研究常见运动医学手术患者的阿片类药物处方实践和阿片类药物消耗率。

资料来源

对电子数据库 EMBASE、MEDLINE 和 PubMed 进行了系统评价,检索时间从数据库建立到 2018 年 12 月。

研究选择

两名调查员独立确定了所有报告关节镜肩、膝或髋关节手术后阿片类药物处方和使用情况的研究。共审查了 119 项研究,其中 8 项符合纳入标准。

研究设计

系统评价。

证据水平

4 级。

数据提取

所开阿片类药物的数量和用量被转换为毫克吗啡当量(MME)进行标准化报告。使用非随机研究方法学指数评估每项合格研究的质量。

结果

共有 8 项研究,包括 816 名平均年龄为 43.8 岁的患者,符合纳入标准。关节镜肩关节、膝关节和髋关节手术后分别为患者开了 610、197 和 613 MME。最终随访时,肩关节、膝关节和髋关节关节镜术后分别有 31%、34%和 64%的处方阿片类药物仍在使用。大多数患者(64%)不知道剩余药物的正确处理方法。接受关节镜肩袖修复术的患者阿片类药物消耗最高(471 MME),其中 1/4 的患者需要续药。

结论

关节镜肩关节、膝关节和髋关节手术中阿片类药物开具过多,术后仍有三分之一以上的阿片类药物未使用。大多数患者不知道剩余阿片类药物的正确处理技术。需要适当的风险分层工具和循证建议,以帮助控制不断增长的阿片类药物危机。

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