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1996 - 2016年丹麦1型和2型糖尿病的患病率、发病率及死亡率

Prevalence, incidence and mortality of type 1 and type 2 diabetes in Denmark 1996-2016.

作者信息

Carstensen Bendix, Rønn Pernille Falberg, Jørgensen Marit Eika

机构信息

Clinical Epidemiology, Steno Diabetes Center Copenhagen, Gentofte, Hovedstaden, Denmark.

Clinical Epidemiology, Steno Diabetes Center Copenhagen, Gentofte, Hovedstaden, Denmark

出版信息

BMJ Open Diabetes Res Care. 2020 May;8(1). doi: 10.1136/bmjdrc-2019-001071.

Abstract

INTRODUCTION

The objective of this study was to give an overview of prevalence, incidence and mortality of type 1 (T1D) and type 2 diabetes (T2D) in Denmark, and their temporal trends.

RESEARCH DESIGN AND METHODS

We constructed a diabetes register from existing population-based healthcare registers, including a classification of patients as T1D or T2D, with coverage from 1996 to 2016. Using complete population records for Denmark, we derived prevalence, incidence, mortality and standardized mortality ratio (SMR).

RESULTS

The overall prevalence of diabetes at 2016 was 0.5% for T1D and 4.4% for T2D, with annual increases since 1996 of 0.5% for T1D and 5.5% for T2D. Incidence rates of T1D decreased by 3.5% per year, with increase for persons under 25 years of age and a decrease for older persons. T2D incidence increased 2.5% per year until 2011, decreased until 2014 and increased after that, similar in all ages. The annual decrease in mortality was 0.3% for T1D and 2.9% for T2D. The mortality rate ratio between T1D and T2D was 1.9 for men and 1.6 for women. SMR decreased annually 2% for T1D and 0.5% for T2D.

CONCLUSIONS

Incidence and prevalence of diabetes is increasing, but mortality among patients with diabetes in Denmark is decreasing faster than the mortality among persons without diabetes. T1D carries a 70% higher mortality than T2D.

摘要

引言

本研究的目的是概述丹麦1型糖尿病(T1D)和2型糖尿病(T2D)的患病率、发病率和死亡率及其时间趋势。

研究设计与方法

我们根据现有的基于人群的医疗保健登记构建了一个糖尿病登记册,包括将患者分类为T1D或T2D,覆盖时间为1996年至2016年。利用丹麦的完整人口记录,我们得出了患病率、发病率、死亡率和标准化死亡率(SMR)。

结果

2016年糖尿病的总体患病率T1D为0.5%,T2D为4.4%,自1996年以来,T1D每年增加0.5%,T2D每年增加5.5%。T1D的发病率每年下降3.5%,25岁以下人群发病率上升,老年人发病率下降。T2D发病率在2011年前每年增加2.5%,2014年前下降,之后上升,各年龄段情况相似。T1D的年死亡率下降0.3%,T2D下降2.9%。T1D与T2D的死亡率之比男性为1.9,女性为1.6。T1D的SMR每年下降2%,T2D每年下降0.5%。

结论

糖尿病的发病率和患病率在上升,但丹麦糖尿病患者的死亡率下降速度比非糖尿病患者的死亡率下降速度更快。T1D的死亡率比T2D高70%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9227/7265004/b9b8896fb83d/bmjdrc-2019-001071f01.jpg

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