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动机访谈增强型行为疗法治疗青少年注意缺陷多动障碍的有效性:一项基于社区的随机试验。

Effectiveness of Motivational Interviewing-Enhanced Behavior Therapy for Adolescents With Attention-Deficit/Hyperactivity Disorder: A Randomized Community-Based Trial.

机构信息

University of Washington School of Medicine, Seattle Children's Research Institute, Seattle; Florida International University Herbert Wertheim College of Medicine, Miami, FL.

Florida International University, Miami.

出版信息

J Am Acad Child Adolesc Psychiatry. 2021 Jun;60(6):745-756. doi: 10.1016/j.jaac.2020.07.907. Epub 2020 Aug 28.

Abstract

OBJECTIVE

This study tests the effectiveness of parent-teen psychotherapy for adolescent attention-deficit/hyperactivity disorder (ADHD) (Supporting Teens' Autonomy Daily [STAND]) versus usual care (UC) in 4 community clinics.

METHOD

A randomized clinical trial was conducted with double randomization of adolescents and therapists to STAND versus UC. Participants were 278 culturally diverse adolescents diagnosed with DSM-5 ADHD at baseline and 82 community therapists. Seven primary outcomes were assessed at baseline (BL), posttreatment (PT; mean = 5.11 months post-BL, SD = 2.26), and follow-up (FU; mean = 9.81 months post-BL, SD = 2.50): inattention (IN; parent/teacher-rated), academics (parent-rated/official records), family functioning (parent/adolescent-rated), and disciplinary records. Treatment engagement indicated consumer fit (eg, number or sessions received, percentage of sessions attended by parent, satisfaction). The impact of treatment on concurrent medication use was also examined. Service delivery features were examined as moderators of outcome.

RESULTS

Intent-to-treat (N = 278) analyses indicated no significant group × time effects. STAND only led to superior outcomes when therapists were licensed (22% of sample) versus unlicensed (parent-rated IN: p < .001, d = 1.08; parent-rated academic impairment: p = .010, d = 1.17). Compared to UC, STAND was associated with greater parent participation (p < .001, d = 0.88) and higher scores on certain indices of parent satisfaction. STAND also was associated with superior medication engagement over time compared to UC (odds ratio = 7.18).

CONCLUSION

Evidence-based psychosocial treatment for adolescent ADHD did not outperform UC on outcome trajectories despite improving some indices of treatment engagement. STAND requires additional adaptation for community contexts.

CLINICAL TRIAL REGISTRATION INFORMATION

STAND Community Trial (STAND); https://clinicaltrials.gov/; NCT02694939.

摘要

目的

本研究旨在检验青少年注意缺陷多动障碍(ADHD)父母-青少年心理治疗(Supporting Teens' Autonomy Daily [STAND])与常规护理(UC)在 4 家社区诊所的疗效。

方法

采用青少年和治疗师双重随机分组的随机临床试验,将 STAND 与 UC 进行比较。参与者为 278 名文化背景多样、在基线时被诊断为 DSM-5 ADHD 的青少年和 82 名社区治疗师。在基线(BL)、治疗后(PT;BL 后平均 5.11 个月,SD=2.26)和随访(FU;BL 后平均 9.81 个月,SD=2.50)时评估了 7 项主要结局指标:注意力不集中(父母/教师评定)、学业成绩(父母评定/官方记录)、家庭功能(父母/青少年评定)和纪律记录。治疗参与度表明了患者的适配性(例如,接受的治疗次数、父母出席的治疗次数百分比、满意度)。还检查了治疗对同时使用药物的影响。检查了服务提供特征作为结果的调节因素。

结果

意向治疗(N=278)分析表明,组间×时间无显著效应。只有当治疗师持照(样本的 22%)而非无证时,STAND 才会导致更好的结果(父母评定的注意力不集中:p<0.001,d=1.08;父母评定的学业受损:p=0.010,d=1.17)。与 UC 相比,STAND 与父母更多的参与(p<0.001,d=0.88)和某些父母满意度指标的更高得分相关。与 UC 相比,STAND 还与随着时间推移更好的药物参与相关(比值比=7.18)。

结论

尽管提高了一些治疗参与度的指标,但针对青少年 ADHD 的循证心理社会治疗并未在结果轨迹上优于 UC。STAND 需要进一步适应社区环境。

临床试验注册信息

STAND 社区试验(STAND);https://clinicaltrials.gov/;NCT02694939。

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