NCLX 火力全开。
NCLX pumps up the heat.
机构信息
Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Dr. Hershey, PA, 17033, USA.
Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Dr. Hershey, PA, 17033, USA.
出版信息
Cell Calcium. 2020 Dec;92:102280. doi: 10.1016/j.ceca.2020.102280. Epub 2020 Aug 28.
Mitochondrial Ca signaling is a well-appreciated regulator of cell metabolism and energy production. A major function of mitochondria in brown adipose tissue (BAT) is thermogenesis. Assali et al. offer new insights into how the mitochondrial Ca extrusion mediator NCLX is crucial for BAT survival and thermogenesis.
线粒体钙信号是细胞代谢和能量产生的一个公认的调节剂。线粒体在棕色脂肪组织 (BAT) 中的一个主要功能是产热。Assali 等人提供了新的见解，即线粒体钙外排介质 NCLX 对 BAT 的存活和产热至关重要。
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