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利用植物提取物及其植物化学物质控制产毒真菌和霉菌毒素。

The use of plant extracts and their phytochemicals for control of toxigenic fungi and mycotoxins.

作者信息

Makhuvele Rhulani, Naidu Kayleen, Gbashi Sefater, Thipe Velaphi C, Adebo Oluwafemi A, Njobeh Patrick B

机构信息

Department of Biotechnology and Food Technology, Faculty of Science, University of Johannesburg, Doornfontein Campus, P.O. Box 17011, Doornfontein Campus, Gauteng, 2028, South Africa.

Laboratório de Ecotoxicologia - Centro de Química e Meio Ambiente - Instituto de Pesquisas Energéticas e Nucleares (IPEN) - Comissão Nacional de Energia Nuclear- IPEN/CNEN-SP, Av. Lineu Prestes, 2242 - Butantã, 05508-000, São Paulo, Brazil.

出版信息

Heliyon. 2020 Oct 22;6(10):e05291. doi: 10.1016/j.heliyon.2020.e05291. eCollection 2020 Oct.

Abstract

Mycotoxins present a great concern to food safety and security due to their adverse health and socio-economic impacts. The necessity to formulate novel strategies that can mitigate the economic and health effects associated with mycotoxin contamination of food and feed commodities without any impact on public health, quality and nutritional value of food and feed, economy and trade industry become imperative. Various strategies have been adopted to mitigate mycotoxin contamination but often fall short of the required efficacy. One of the promising approaches is the use of bioactive plant components/metabolites synergistically with mycotoxin-absorbing components in order to limit exposure to these toxins and associated negative health effects. In particular, is the fabrication of β-cyclodextrin-based nanosponges encapsulated with bioactive compounds of plant origin to inhibit toxigenic fungi and decontaminate mycotoxins in food and feed without leaving any health and environmental hazard to the consumers. The present paper reviews the use of botanicals extracts and their phytochemicals coupled with β-cyclodextrin-based nanosponge technology to inhibit toxigenic fungal invasion and detoxify mycotoxins.

摘要

由于霉菌毒素对健康和社会经济产生不利影响,因此它们对食品安全和保障构成了重大担忧。制定新策略以减轻与食品和饲料商品霉菌毒素污染相关的经济和健康影响,同时又不对食品和饲料的公共卫生、质量和营养价值、经济及贸易行业造成任何影响,已成为当务之急。人们已采取各种策略来减轻霉菌毒素污染,但往往达不到所需的效果。一种有前景的方法是将生物活性植物成分/代谢物与霉菌毒素吸收成分协同使用,以限制对这些毒素的接触以及相关的负面健康影响。特别是,制备包封有植物源生物活性化合物的β-环糊精基纳米海绵,以抑制产毒真菌并去除食品和饲料中的霉菌毒素,而不会给消费者带来任何健康和环境危害。本文综述了植物提取物及其植物化学物质与β-环糊精基纳米海绵技术结合使用以抑制产毒真菌入侵和去除霉菌毒素的情况。

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