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10 kHz 脊髓刺激治疗后上肢和颈部疼痛患者的疼痛缓解和阿片类药物使用:美国研究的亚组分析。

Pain relief and opioid usage in upper limb and neck pain patients after 10-kHz spinal cord stimulation treatment: subanalysis of USA studies.

机构信息

IPM Medical Group Inc., Walnut Creek, CA 94598, USA.

Millennium Pain Center, Bloomington, IL 61704, USA.

出版信息

Pain Manag. 2021 Mar;11(2):133-143. doi: 10.2217/pmt-2020-0074. Epub 2020 Nov 13.

Abstract

It is argued that chronic pain patients who reduce/eliminate their opioids may have compromised pain relief. This study therefore aimed to analyze if reduced opioid consumption associated with 10-kHz spinal cord stimulation adversely affected pain relief. analysis was performed on data from two prospective studies in subjects with upper limbs and neck pain conducted in USA. A 10-kHz spinal cord stimulation treatment was associated with reduction in mean visual analog scale scores for upper limbs and neck pain and mean daily opioid consumption. Pain scores decreased in subjects who decreased opioid use and in those who maintained/increased use. Opioid reduction and pain relief was also achieved in subjects taking >90 mg morphine equivalents of opioids at baseline.

摘要

有人认为,减少/消除阿片类药物的慢性疼痛患者可能会影响疼痛缓解。因此,本研究旨在分析与 10 kHz 脊髓刺激相关的阿片类药物消耗减少是否会对疼痛缓解产生不利影响。分析基于在美国进行的两项针对上肢和颈部疼痛患者的前瞻性研究的数据进行。10 kHz 脊髓刺激治疗与上肢和颈部疼痛的平均视觉模拟评分以及平均每日阿片类药物消耗量的降低相关。减少阿片类药物使用的患者和维持/增加使用的患者的疼痛评分均降低。基线时服用 >90 毫克吗啡等效阿片类药物的患者也实现了阿片类药物的减少和疼痛缓解。

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