University of Glasgow, Glasgow, United Kingdom.
NHS Lanarkshire, Lanarkshire, United Kingdom.
PLoS One. 2020 Dec 8;15(12):e0243639. doi: 10.1371/journal.pone.0243639. eCollection 2020.
Studies on the impacts of child maltreatment (CM) have been conducted in diverse areas. Mechanistic understanding of the complex interplay between factors is lacking. Hallmarking is an approach which identifies common factors across studies and highlights the most robust findings.
In a review of systematic reviews and meta-analyses, we addressed the following questions: 1) What are the hallmarks associated with exposure to CM across the bio-ecological spectrum? 2) What is the strength of evidence to support each hallmark? 3) What are the gaps that future research should address?
A comprehensive literature search was carried out to find relevant systematic reviews or meta-analyses. 269 articles were read in full and 178 articles, encompassing more than 6000 original papers, were included in the final synthesis. All reviews were independently rated for quality by at least 2 reviewers using AMSTAR-2.
Of 178 review articles, 6 were rated as high quality (all meta-analyses) and 46 were rated as medium quality. Most were from high income countries.
Based on the most commonly reported high-quality research findings we propose that the hallmarks of exposure to child maltreatment are: Increased risk of psychopathology; Increased risk of obesity; Increased risk of high- risk sexual behaviours, Increased risk of smoking; and Increased risk of child maltreatment in children with disabilities. Research gaps include a lack of focus on complexity and resilience. Little can be concluded about directions of causality or mechanisms. Adequately powered prospective studies are required to move the field forward.
儿童虐待(CM)的影响研究在不同领域都有进行。但对这些因素之间复杂相互作用的机制理解还很缺乏。标志法是一种识别研究中共同因素并突出最有力发现的方法。
在对系统评价和荟萃分析的综述中,我们提出了以下问题:1)在生物-生态谱中,与暴露于 CM 相关的标志有哪些?2)支持每个标志的证据强度如何?3)未来研究应该解决哪些空白?
进行了全面的文献检索,以查找相关的系统评价或荟萃分析。阅读了 269 篇全文,并纳入了最终综合分析的 178 篇文章,这些文章涵盖了 6000 多篇原始论文。所有的综述都由至少 2 位评审员使用 AMSTAR-2 进行独立的质量评估。
在 178 篇综述文章中,有 6 篇被评为高质量(均为荟萃分析),46 篇被评为中等质量。大多数研究来自高收入国家。
根据最常报道的高质量研究结果,我们提出暴露于儿童虐待的标志有:增加患精神病理学的风险;增加肥胖的风险;增加高危性行为的风险;增加吸烟的风险;增加残疾儿童遭受虐待的风险。研究空白包括缺乏对复杂性和恢复力的关注。关于因果关系或机制几乎没有结论。需要进行充分的前瞻性研究来推动该领域的发展。