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一款具有正念训练功能的智能手机应用用于青少年戒烟的可行性:渴望戒烟(C2Q)-青少年版。

Feasibility of a Smartphone App with Mindfulness Training for Adolescent Smoking Cessation: Craving to Quit (C2Q)-Teen.

作者信息

Pbert Lori, Druker Susan, Crawford Sybil, Frisard Christine, Trivedi Michelle, Osganian Stavroula K, Brewer Judson

机构信息

Division of Preventive and Behavioral Medicine, 368 Plantation Street, University of Massachusetts Medical School, Worcester, MA USA.

Graduate School of Nursing, 55 Lake Avenue North, University of Massachusetts Medical School, Worcester, MA USA.

出版信息

Mindfulness (N Y). 2020 Mar;11(3):720-733. doi: 10.1007/s12671-019-01273-w. Epub 2019 Dec 20.

Abstract

OBJECTIVES

The use of mobile technology for smoking cessation holds promise for adolescents, who do not typically access traditional treatments, but most are not grounded in theory or mechanism. Operant conditioning theory suggests an addictive smoking loop is formed between nicotine use and affective states, leading to habitual cue-induced craving and automatic behavior; mindfulness training may bring automated smoking behavior into awareness, so smokers may work mindfully with cravings. Mindfulness training delivered via smartphone technology therefore has potential to help adolescent smokers break this addictive loop and quit smoking. This pair-matched cluster-randomized controlled school-based pilot study evaluated program feasibility and preliminary smoking outcomes in relation to intervention engagement.

METHODS

Six high schools were pair matched and randomly assigned to one of three interventions: (1) mindfulness training delivered via mobile smoking cessation application (Craving to Quit, C2Q), (2) NCI's QuitSTART smoking cessation application (NCI), and (3) written cessation materials (Materials). Adolescents (n = 146) smoking 5 or more cigarettes per day were recruited. Interventions were implemented over four weeks and study assessments were collected at baseline and 3- and 6- month follow-up, including self-reported 7-day point prevalence abstinence, program usage, smoking-related measures, and psychosocial factors.

RESULTS

Overall cotinine-validated abstinence at 6 months was 15.8% and was similar between conditions. Odds of abstinence increased with each quartile increase in app/materials use with no significant differences between conditions (OR=1.60 (C2Q), 1.66 (Materials), and 2.69 (NCI)). Of participants still smoking at 6 months, for each quartile increase in engagement the number of cigarettes smoked in the previous 7 days showed a significantly greater decline in the C2Q condition (-5.71) compared to the Materials (-0.95) and NCI (+7.73) condition (p=0.02 for differences between conditions).

CONCLUSIONS

Cotinine-validated abstinence was similar between intervention conditions and tended to increase with greater engagement in each condition. Greater C2Q app engagement among continuing smokers was associated with a significantly greater decline in number of cigarettes smoked compared to the other conditions. The Craving to Quit (C2Q) mobile smoking cessation application with mindfulness training was feasible to use and has promise in assisting adolescents to quit or decrease cigarette smoking.

CLINICAL TRIAL REGISTRATION

Developing a Smartphone App with Mindfulness Training for Teen Smoking Cessation: ClinicalTrials.gov Identifier: NCT02218281.

摘要

目的

利用移动技术帮助青少年戒烟具有一定前景,因为青少年通常无法获得传统治疗,但大多数此类技术缺乏理论或机制基础。操作性条件反射理论表明,在尼古丁使用和情感状态之间形成了一个成瘾性吸烟循环,导致习惯性的线索诱导渴望和自动行为;正念训练可能会使自动吸烟行为进入意识层面,这样吸烟者就可以有意识地应对渴望。因此,通过智能手机技术提供正念训练有潜力帮助青少年吸烟者打破这种成瘾循环并戒烟。这项配对匹配的整群随机对照学校试点研究评估了该项目的可行性以及与干预参与度相关的初步吸烟结果。

方法

六所高中进行配对匹配,并随机分配到三种干预措施之一:(1)通过移动戒烟应用程序(渴望戒烟,C2Q)提供正念训练,(2)美国国立癌症研究所(NCI)的戒烟启动(QuitSTART)应用程序(NCI),以及(3)书面戒烟材料(材料)。招募了每天吸烟5支或更多支的青少年(n = 146)。干预措施实施四周,在基线以及3个月和6个月随访时收集研究评估数据,包括自我报告的7天点患病率戒烟情况、项目使用情况、吸烟相关指标和心理社会因素。

结果

6个月时经可替宁验证的总体戒烟率为15.8%,各条件之间相似。随着应用程序/材料使用量每增加一个四分位数,戒烟几率增加,各条件之间无显著差异(比值比=1.60(C2Q),1.66(材料),2.69(NCI))。在6个月时仍在吸烟的参与者中,与材料组(-0.95)和NCI组(+7.73)相比,C2Q组参与者的参与度每增加一个四分位数,前7天的吸烟量下降幅度显著更大(-5.71)(组间差异p = 0.02)。

结论

各干预条件下经可替宁验证的戒烟率相似,且在每种条件下随着参与度的提高往往会增加。与其他条件相比,持续吸烟者中C2Q应用程序的参与度更高与吸烟量显著更大幅度的下降相关。带有正念训练的渴望戒烟(C2Q)移动戒烟应用程序使用起来可行,在帮助青少年戒烟或减少吸烟方面有前景。

临床试验注册

开发一款用于青少年戒烟的正念训练智能手机应用程序:ClinicalTrials.gov标识符:NCT02218281。

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