Parisi Giuseppe Fabio, Indolfi Cristiana, Decimo Fabio, Leonardi Salvatore, Miraglia Del Giudice Michele
Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Department of Woman, Child and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Front Pediatr. 2020 Dec 14;8:616622. doi: 10.3389/fped.2020.616622. eCollection 2020.
COVID-19 is less serious in children than in adults. However, respiratory management dominates the clinical picture of hospitalized COVID-19 even in children. In some case series, deterioration of the clinical picture wherein dyspnea, cyanosis, and the onset of acute respiratory distress syndrome (ARDS) emerged ~8-10 days after the onset of SARS-CoV-2 infection, which could rapidly progress to multiple organ failure and death. This review aimed to evaluate the characteristics of COVID-19 pneumonia in pediatric populations, beginning from its etiology and pathological mechanisms and closing with its clinical management.
新型冠状病毒肺炎(COVID-19)在儿童中比在成人中症状较轻。然而,即使在儿童中,呼吸管理也是COVID-19住院患者临床表现的主要方面。在一些病例系列中,临床表现恶化,其中呼吸困难、发绀和急性呼吸窘迫综合征(ARDS)在严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染发病后约8-10天出现,这可能迅速发展为多器官功能衰竭和死亡。本综述旨在评估儿童COVID-19肺炎的特征,从其病因和病理机制入手,以其临床管理结束。