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袖状胃切除术是导致胃食管反流病的最常见原因,相较于其他减重手术而言。

Sleeve Gastrectomy Is the Most Common Cause of Gastroesophageal Reflux Disease in Comparison with Other Bariatric Operations.

机构信息

Department of General Surgery, Bariatric Unit, AZ Sint Jan Hospital, Bruges, Belgium,

Intern physician, Hadassah Medical Center, Jerusalem, Israel.

出版信息

Dig Dis. 2021;39(5):462-466. doi: 10.1159/000514377. Epub 2021 Jan 13.

Abstract

INTRODUCTION

Gastroesophageal reflux disease (GERD) is one of the complications of bariatric operations that might affect the quality of life. We aim to perform a retrospective cohort study to determine the incidence of symptomatic GERD following different types of bariatric surgery and which operations are considered a contraindication of GERD. Besides, we are attempting to identify the risk factors of GERD after bariatric surgery.

METHODS

Medical records of 729 patients who had undergone bariatric operations between January 2010 and June 2019 at the Shamir (Assaf Harofeh) Medical Center were reviewed.

RESULTS

There was a significant difference between the type of bariatric procedure and the incidence of GERD symptoms after the operation. The incidence of symptomatic GERD in patients who underwent sleeve gastrectomy (SG) was 39.9% (p = 0.0131). This was significantly higher compared to 16.4% following Roux-en-Y gastric bypass, 23.4% following laparoscopic adjustable gastric band, and 11% following one anastomosis gastric bypass. 113 patients out of 718 had a positive swallow test, and of these patients, 71 developed GERD symptoms postoperatively without correlation to the degree of reflux at the swallow test but with statistically significant correlation to the type of operation especially for SG (p value < 0.001), and to our knowledge, this was never reported in the literature.

CONCLUSION

SG is a good bariatric procedure option but should be considered carefully in asymptomatic patients with reflux at contrast swallow study and symptomatic GERD patients preoperatively because of high levels of symptomatic GERD postoperatively. Asymptomatic reflux at contrast swallow study preoperatively could be considered a risk factor for GERD after the operation. More studies are needed to be performed on this subject with the addition of postoperative contrast swallow test and pH monitoring preoperatively and postoperatively.

摘要

简介

胃食管反流病(GERD)是肥胖手术的并发症之一,可能会影响生活质量。我们旨在进行回顾性队列研究,以确定不同类型的减重手术后出现有症状的 GERD 的发生率,以及哪些手术被认为是 GERD 的禁忌症。此外,我们试图确定减重手术后 GERD 的危险因素。

方法

回顾了 2010 年 1 月至 2019 年 6 月期间在 Shamir(Assaf Harofeh)医疗中心接受减重手术的 729 名患者的病历。

结果

减重手术类型与术后 GERD 症状的发生率有显著差异。行袖状胃切除术(SG)的患者中,有症状的 GERD 发生率为 39.9%(p=0.0131)。与 Roux-en-Y 胃旁路术的 16.4%、腹腔镜可调胃带的 23.4%和单吻合口胃旁路术的 11%相比,这一比例显著升高。在 718 名有吞咽试验阳性的患者中,有 113 名患者术后出现 GERD 症状,与吞咽试验中的反流程度无关,但与手术类型有统计学显著相关性,特别是与 SG(p 值<0.001),据我们所知,这在文献中从未报道过。

结论

SG 是一种很好的减重手术选择,但对于在对比吞咽研究中无症状的反流患者和术前有症状的 GERD 患者,应慎重考虑,因为术后会出现高水平的有症状的 GERD。术前对比吞咽研究中的无症状反流可被视为术后 GERD 的危险因素。需要更多的研究来对此进行研究,包括术前和术后的对比吞咽试验和 pH 监测。

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