中国湖北省东南部人群中弓形虫感染的血清流行率。

Seroprevalence of Toxoplasma gondii infection in people in southeast Hubei province, China.

机构信息

Hubei Key Laboratory for Kidney Disease Pathogenesis and Intervention, Hubei Polytechnic University, Medical School, Huangshi 435003, Hubei, China.

College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, 430070, China.

出版信息

Trop Biomed. 2020 Jun 1;37(2):452-457.

PMID:33612814

Abstract

Toxoplasma gondii is a world-widely spread zoonotic parasite. However, scarce knowledge is known about the prevalence of T. gondii infection in people in Hubei province, China. This study herein was to perform epidemiological investigation of T. gondii infection in people in this region. A total 12527 blood samples were obtained during 2015-2018, and were assayed for T. gondii antibodies of IgG and IgM, respectively by employing an indirect hemagglutination test (IHA). The results discovered that the prevalence of T. gondii in people was 2.44% and 6.1%, respectively based on antibodies of IgG and IgM, respectively. The prevalence was ranged from 0.3% to 5.4% during 2015-2018 based on IgM antibodies. For genders, the prevalence was 0.7% and 2.6% in males and females, respectively based on IgM antibodies. In different years, the prevalence was ranged from 4.9% to 14.0% based on IgG antibodies. The prevalence of T. gondii was 4.9% and 6.6% in males and femalesy based on IgG antibodies. The current results may be helpful for the implementation of preventive measures against Toxoplasma infection among people living in this region.

摘要

刚地弓形虫是一种广泛分布于全世界的动物源性寄生虫。然而，对于中国湖北省人群中刚地弓形虫感染的流行情况，人们知之甚少。本研究旨在对该地区人群进行刚地弓形虫感染的流行病学调查。在 2015 年至 2018 年间共采集了 12527 份血样，分别采用间接血凝试验（IHA）检测 IgG 和 IgM 抗体，以检测 T. gondii 抗体。结果发现，人群中 T. gondii 的 IgG 和 IgM 抗体阳性率分别为 2.44%和 6.1%。2015 年至 2018 年间，IgM 抗体阳性率范围为 0.3%至 5.4%。对于性别而言，IgM 抗体阳性率男性为 0.7%，女性为 2.6%。不同年份 IgG 抗体阳性率范围为 4.9%至 14.0%。IgG 抗体阳性率男性为 4.9%，女性为 6.6%。本研究结果可能有助于实施该地区人群针对弓形虫感染的预防措施。