Coêlho Matheus Diniz Gonçalves, Maciel Lucas Tobias Rodrigues, de Fátima Kieko Ozaki Thaís, Silva Maria Eduarda Godoi, Bozo Lilian Saito Ormachea, Consoli Yumi Ando, Pereira-Maciel Fernanda Bueno Sant'Anna, Akisue Gokithi, da Silva-Coêlho Francine Alves
Centro Universitário FUNVIC, Pindamonhangaba, São Paulo Brazil.
Laboratório de Parasitologia e Malacologia, Centro Universitário FUNVIC, Pindamonhangaba, São Paulo Brazil.
J Parasit Dis. 2021 Mar;45(1):252-257. doi: 10.1007/s12639-020-01302-9. Epub 2020 Nov 7.
Nematodes of the Ancylostomidae family consist of important parasitic species. The control of such parasitosis represents an important challenge, given the constant high rate of reinfection of some hosts, among which the domestic dog, as well as the high environmental contamination. Another factor that can have a negative influence is the toxicity of the chemicals used for environmental decontamination, highlighting the need to design research to identify new control strategies for this parasitosis, among which the use of plant extracts. Thus, the objective of this research was to evaluate the toxicity and ovicidal activity of hydroalcoholic extracts obtained by percolation of three plants: L., var splendens (Bojer ex Hook.) Ursch & Leandri and Boiss, against spp. In addition, these extracts were tested at different concentrations for toxicity against L. and L. It was observed that the hydroalcoholic extract of all plant species evaluated induced moderate ovicide activity at all the tested concentration, with emphasis on , which was the only plant species that presented significantly low toxicity in the concentration of 12.5 µL/mL when compared to the other species evaluated.
钩口科线虫包含重要的寄生虫种类。鉴于一些宿主(包括家犬)的再感染率持续居高不下以及环境污染严重,控制此类寄生虫病是一项重大挑战。另一个可能产生负面影响的因素是用于环境净化的化学物质的毒性,这凸显了开展研究以确定这种寄生虫病新控制策略的必要性,其中包括使用植物提取物。因此,本研究的目的是评估通过渗漉三种植物(即[植物一学名]、[植物二学名]和[植物三学名])获得的水醇提取物对[寄生虫学名]的毒性和杀卵活性。此外,还对这些提取物在不同浓度下对[其他寄生虫学名1]和[其他寄生虫学名2]的毒性进行了测试。结果发现,所有评估植物种类的水醇提取物在所有测试浓度下均诱导出中等程度的杀卵活性,其中[某种植物]尤为突出,与其他评估物种相比,它是唯一在浓度为12.5微升/毫升时毒性显著较低的植物种类。