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阿片类药物过度处方和整形与重建外科患者的特定手术阿片类药物消费模式。

Opioid Overprescribing and Procedure-Specific Opioid Consumption Patterns for Plastic and Reconstructive Surgery Patients.

机构信息

From the Department of Plastic and Reconstructive Surgery, The Ohio State University Medical Center; and the Center for Regenerative Medicine, Nationwide Children's Hospital.

出版信息

Plast Reconstr Surg. 2021 Apr 1;147(4):669e-679e. doi: 10.1097/PRS.0000000000007782.

Abstract

BACKGROUND

Opioid prescribing practices contribute to opioid misuse, dependency, and diversion. There are currently no comprehensive and quantitative evidence-based guidelines that give procedure-specific recommendations regarding opioid prescribing in plastic surgery.

METHODS

A retrospective review of 479 plastic surgery patients encompassing 23 different plastic surgery procedure categories was performed. Opioid prescribing patterns and patient-reported opioid use at 1 and 3 months postoperatively are reported.

RESULTS

Opioid overprescribing was common, averaging an excess of 13 pills per patient across all procedure categories (prescribed versus consumed, 25.4 ± 23.1 versus 12.1 ± 19.7; p = 3.0 × 10-19), with a total excess of 5895 pills (30,967 oral morphine equivalents) for the study's sample. Fifty-two percent of all opioid pills prescribed went unused. Opioid consumption ranged between four and 37 pills across procedure categories. A greater proportion of patients who reported a history of preoperative opioid use were still using opioids at the time of their 1-month and 3-month follow-up appointments (62 percent versus 9 percent at 1 month, and 31 percent versus 1 percent at 3 months). Most patients (83 percent) did not store opioids in a locked location, and 64 percent did not dispose of opioids at 1 month.

CONCLUSIONS

Opioids are commonly overprescribed by plastic surgery providers. This study determined procedure-specific opioid consumption patterns, which can help providers reduce opioid waste. In addition, patients do not properly store or dispose of opioids, demonstrating the need for better patient education.

摘要

背景

阿片类药物的处方实践导致阿片类药物的滥用、依赖和转移。目前没有全面和基于证据的综合指南,为整形外科中的阿片类药物处方提供具体的程序建议。

方法

对 479 名整形外科患者进行回顾性研究,涵盖 23 种不同的整形外科手术类别。报告了阿片类药物的处方模式和患者术后 1 个月和 3 个月的阿片类药物使用情况。

结果

阿片类药物的过度处方很常见,所有手术类别平均每个患者超过 13 片(规定剂量与实际消耗剂量,25.4 ± 23.1 与 12.1 ± 19.7;p = 3.0×10-19),研究样本总共有 5895 片(30967 个口服吗啡当量)的阿片类药物过剩。所有开处的阿片类药物中有 52%未被使用。阿片类药物的消耗量在手术类别之间从 4 到 37 片不等。报告有术前阿片类药物使用史的患者中,有更大比例的患者在 1 个月和 3 个月的随访时仍在使用阿片类药物(62%与 1 个月时的 9%,31%与 3 个月时的 1%)。大多数患者(83%)没有将阿片类药物存放在上锁的地方,64%的患者在 1 个月时没有处理掉阿片类药物。

结论

整形外科医生经常过度开具阿片类药物处方。本研究确定了具体手术的阿片类药物消耗模式,这可以帮助医生减少阿片类药物的浪费。此外,患者没有正确储存或处理阿片类药物,这表明需要更好的患者教育。

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