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常见感染性疾病中短程抗生素的合理应用:美国医师学院的最佳实践建议。

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians.

机构信息

University of Alabama at Birmingham, Birmingham, Alabama (R.A.L.).

Birmingham Veterans Affairs Medical Center and University of Alabama at Birmingham, Birmingham, Alabama (R.M.C.).

出版信息

Ann Intern Med. 2021 Jun;174(6):822-827. doi: 10.7326/M20-7355. Epub 2021 Apr 6.

Abstract

DESCRIPTION

Antimicrobial overuse is a major health care issue that contributes to antibiotic resistance. Such overuse includes unnecessarily long durations of antibiotic therapy in patients with common bacterial infections, such as acute bronchitis with chronic obstructive pulmonary disease (COPD) exacerbation, community-acquired pneumonia (CAP), urinary tract infections (UTIs), and cellulitis. This article describes best practices for prescribing appropriate and short-duration antibiotic therapy for patients presenting with these infections.

METHODS

The authors conducted a narrative literature review of published clinical guidelines, systematic reviews, and individual studies that addressed bronchitis with COPD exacerbations, CAP, UTIs, and cellulitis. This article is based on the best available evidence but was not a formal systematic review. Guidance was prioritized to the highest available level of synthesized evidence.

BEST PRACTICE ADVICE 1:

BEST PRACTICE ADVICE 2:

BEST PRACTICE ADVICE 3:

BEST PRACTICE ADVICE 4:

摘要

描述

抗菌药物过度使用是一个主要的医疗保健问题,它导致了抗生素耐药性的产生。这种过度使用包括在患有常见细菌感染(如慢性阻塞性肺疾病(COPD)加重的急性支气管炎、社区获得性肺炎(CAP)、尿路感染(UTIs)和蜂窝织炎)的患者中不必要地延长抗生素治疗时间。本文描述了为出现这些感染的患者开具适当和短疗程抗生素治疗的最佳实践。

方法

作者对已发表的临床指南、系统评价和针对 COPD 加重性支气管炎、CAP、UTIs 和蜂窝织炎的单项研究进行了叙述性文献回顾。本文基于现有最佳证据,但不是正式的系统评价。根据可获得的最高级别综合证据对指南进行了优先级排序。

最佳实践建议 1:

最佳实践建议 2:

最佳实践建议 3:

最佳实践建议 4:

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