Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.
CSIR-Institute of Genomics and Integrative Biology, New Delhi, 110007, India.
Environ Sci Pollut Res Int. 2021 Sep;28(33):45853-45866. doi: 10.1007/s11356-021-13600-7. Epub 2021 Apr 21.
The present study explored the association between daily ambient air pollution and daily emergency room (ER) visits due to acute respiratory symptoms in children of Delhi. The daily counts of ER visits (ERV) of children (≤15 years) having acute respiratory symptoms were obtained from two hospitals of Delhi for 21 months. Simultaneously, data on daily concentrations of particulate matter (PM and PM), nitrogen dioxide (NO), sulfur dioxide (SO), carbon monoxide (CO), and ozone (O) and weather variables were provided by the Delhi Pollution Control Committee. K-means clustering with time-series approach and multi-pollutant generalized additive models with Poisson link function was used to estimate the 0-6-day lagged change in daily ER visits with the change in multiple pollutants levels. Out of 1,32,029 children screened, 19,120 eligible children having acute respiratory symptoms for ≤2 weeks and residing in Delhi for the past 4 weeks were enrolled. There was a 29% and 21% increase in ERVs among children on high and moderate level pollution cluster days, respectively, compared to low pollution cluster days on the same day and previous 1-6 days of exposure to air pollutants. There was percentage increase (95% CI) 1.50% (0.76, 2.25) in ERVs for acute respiratory symptoms for 10 μg/m increase of NO on previous day 1, 46.78% (21.01, 78.05) for 10 μg/m of CO on previous day 3, and 13.15% (9.95, 16.45) for 10 μg/m of SO on same day of exposure. An increase in the daily ER visits of children for acute respiratory symptoms was observed after increase in daily ambient air pollution levels in Delhi.
本研究探讨了德里儿童因急性呼吸道症状每日前往急诊室(ER)就诊与每日环境空气污染之间的关联。通过德里污染控制委员会,获得了德里两家医院 21 个月内患有急性呼吸道症状的儿童(≤15 岁)每日 ER 就诊(ERV)的计数。同时,提供了每日颗粒物(PM 和 PM)、二氧化氮(NO)、二氧化硫(SO)、一氧化碳(CO)和臭氧(O)浓度以及气象变量的数据。采用时间序列聚类和多污染物广义加性模型与泊松链接函数相结合的方法,估计了在多污染物水平变化的情况下,每日 ER 就诊的 0-6 天滞后变化。在筛选出的 132,029 名儿童中,纳入了 19,120 名患有急性呼吸道症状且≤2 周且在过去 4 周内居住在德里的合格儿童。与低污染集群日相比,在高污染集群日和中污染集群日,儿童 ERV 分别增加了 29%和 21%。与前一天和前 1-6 天暴露于空气污染物相比,儿童 ERV 因前一天 10μg/m3 的 NO 增加而增加了 1.50%(0.76,2.25),前一天 3 的 CO 增加了 46.78%(21.01,78.05),暴露当天的 SO 增加了 13.15%(9.95,16.45)。在德里每日环境空气污染水平升高后,观察到儿童因急性呼吸道症状而每日前往急诊室就诊的次数增加。