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尾侧发育不全:理解广泛临床谱的基础

Caudal Agenesis : Understanding the Base of the Wide Clinical Spectrum.

作者信息

Lee Ji Yeoun, Shim Youngbo, Wang Kyu-Chang

机构信息

Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, Korea.

Department of Anatomy, Seoul National University College of Medicine, Seoul, Korea.

出版信息

J Korean Neurosurg Soc. 2021 May;64(3):380-385. doi: 10.3340/jkns.2021.0025. Epub 2021 Apr 29.

Abstract

Caudal agenesis refers to the congenital malformation with the essential feature of the agenesis of the sacrococcygeal bone. It is associated with various types of spinal cord anomaly as well as with complex anomalies of genitourinary or gastrointestinal system. The wide spectrum of the disease can be attributed to its pathoembryological origin, the secondary neurulation. This review presents the definition, etiology, classification, and clinical features of the disease.

摘要

尾椎发育不全是指以骶尾骨发育不全为主要特征的先天性畸形。它与各种类型的脊髓异常以及泌尿生殖系统或胃肠道的复杂异常有关。该疾病的广泛谱系可归因于其病理胚胎学起源,即继发性神经胚形成。本文综述了该疾病的定义、病因、分类和临床特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e98/8128516/d229a86f0ff0/jkns-2021-0025f1.jpg

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