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与德尔塔变异株相比,报告的 COVID-19 病例中感染 SARS-CoV-2 奥密克戎 BA.1 变异株的住院风险降低,挪威,2021 年 12 月至 2022 年 1 月。

Reduced risk of hospitalisation among reported COVID-19 cases infected with the SARS-CoV-2 Omicron BA.1 variant compared with the Delta variant, Norway, December 2021 to January 2022.

机构信息

Department of Infection Control and Preparedness, Norwegian Institute of Public Health, Oslo, Norway.

Department of Infection Control and Vaccines, Norwegian Institute of Public Health, Oslo, Norway.

出版信息

Euro Surveill. 2022 Jan;27(4). doi: 10.2807/1560-7917.ES.2022.27.4.2200077.

Abstract

We included 39,524 COVID-19 Omicron and 51,481 Delta cases reported in Norway from December 2021 to January 2022. We estimated a 73% reduced risk of hospitalisation (adjusted hazard ratio: 0.27; 95% confidence interval: 0.20-0.36) for Omicron compared with Delta. Compared with unvaccinated groups, Omicron cases who had completed primary two-dose vaccination 7-179 days before diagnosis had a lower reduced risk than Delta (66% vs 93%). People vaccinated with three doses had a similar risk reduction (86% vs 88%).

摘要

我们纳入了 2021 年 12 月至 2022 年 1 月期间挪威报告的 39524 例 COVID-19 奥密克戎和 51481 例德尔塔病例。我们估计奥密克戎导致住院的风险降低了 73%(调整后的危害比:0.27;95%置信区间:0.20-0.36),与德尔塔相比。与未接种疫苗的人群相比,在诊断前 7-179 天完成两剂初级疫苗接种的奥密克戎病例的风险降低幅度低于德尔塔(66%比 93%)。接种三剂疫苗的人群的风险降低幅度相似(86%比 88%)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ceaf/8796289/4638c8c0790e/2200077-f1.jpg

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