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乳房成形术后疼痛的神经阻滞:随机对照研究的荟萃分析

Nerve Block on Pain After Mammaplasty: A Meta-Analysis of randomized controlled studies.

作者信息

Li Xiaoxia, Li Ying

机构信息

Burn Plastic and Cosmetic Surgery Department, Bayannur City Hospital, Inner Mongolia, People's Republic of China.

出版信息

Plast Surg (Oakv). 2022 Feb;30(1):32-38. doi: 10.1177/2292550320969648. Epub 2020 Nov 19.

Abstract

BACKGROUND

Nerve block showed some potential in alleviating pain after mammaplasty. This systematic review and meta-analysis was conducted to investigate the efficacy of nerve block for pain control after mammaplasty.

METHODS

The databases including PubMed, Embase, Web of Science, EBSCO, and Cochrane library databases were systematically searched for collecting the randomized controlled trials (RCTs) regarding the impact of nerve block on pain intensity after mammaplasty.

RESULTS

This meta-analysis included 4 RCTs. Compared with control group after mammaplasty, nerve block resulted in remarkably reduced pain scores at 1 hour (mean difference [MD] = -1.84; 95% CI = -2.49 to -1.20; < .00001), 3 hours (MD = -1.04; 95% CI = -1.47 to -0.62; < .00001), 6 hours (MD = -0.96; 95% CI = -1.48 to -0.43; = .0004), and analgesic consumption (standard mean difference = -1.27; 95% CI = -1.73 to -0.82; < .00001), but showed no significant impact on pain scores within 24 hours (MD = -0.31; 95% CI = -1.05 to 0.43; = .41).

CONCLUSIONS

Nerve block was associated with substantially reduced pain intensity after mammaplasty.

摘要

背景

神经阻滞在减轻乳房整形术后疼痛方面显示出一定潜力。本系统评价和荟萃分析旨在研究神经阻滞对乳房整形术后疼痛控制的疗效。

方法

系统检索包括PubMed、Embase、Web of Science、EBSCO和Cochrane图书馆数据库在内的数据库,以收集关于神经阻滞对乳房整形术后疼痛强度影响的随机对照试验(RCT)。

结果

该荟萃分析纳入了4项RCT。与乳房整形术后的对照组相比,神经阻滞在术后1小时(平均差[MD]=-1.84;95%置信区间[CI]=-2.49至-1.20;P<.00001)、3小时(MD=-1.04;95%CI=-1.47至-0.62;P<.00001)、6小时(MD=-0.96;95%CI=-1.48至-0.43;P=.0004)时疼痛评分显著降低,镇痛药物消耗量也显著降低(标准化平均差=-1.27;95%CI=-1.73至-0.82;P<.00001),但对24小时内的疼痛评分无显著影响(MD=-0.31;95%CI=-1.05至0.43;P=.41)。

结论

神经阻滞与乳房整形术后疼痛强度的显著降低相关。

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