Mahesha Priyanka, Shetty Nitinkumar S, Kulkarni Suresh D
Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, India.
Department of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
J Fluoresc. 2022 May;32(3):835-862. doi: 10.1007/s10895-022-02900-x. Epub 2022 Feb 24.
Disclosure of new molecular probes as chromogenic and fluorogenic cation sensors is scientifically exigent work. Recently chalcone derivatives gained more attention because of their structural variability. A suitable donor and acceptor groups separated by delocalized π-orbitals display excellent chromogenic and fluorogenic properties because of intramolecular charge transfer (ICT). These designed molecular frameworks provide the coordination sites to the incoming metal ions results in small changes in the optical properties. In a typical sensing behavior, coordination leads to a large conjugation plane with the probe resulted in hypo/hyperchromic shifts or red/blue shifts. In this review, we tried to converge the reported chalcone-derived sensors and explored the design, synthesis, metal ion sensing mechanism, and practical application of the probes. We expect that this review gives a basic outline for researchers to explore the field of chalcone-based sensors further.
公开新型分子探针作为显色和荧光阳离子传感器是一项科学上急需开展的工作。最近,查尔酮衍生物因其结构的多样性而受到更多关注。由离域π轨道隔开的合适供体和受体基团由于分子内电荷转移(ICT)而表现出优异的显色和荧光特性。这些设计的分子框架为进入的金属离子提供了配位位点,导致光学性质发生微小变化。在典型的传感行为中,配位会导致与探针形成大的共轭平面,从而产生减色/增色位移或红移/蓝移。在本综述中,我们试图汇集已报道的查尔酮衍生传感器,并探讨这些探针的设计、合成、金属离子传感机制及实际应用。我们期望本综述能为研究人员进一步探索基于查尔酮的传感器领域提供一个基本框架。