Carella Michele, Beck Florian, Piette Nicolas, Denys Sébastien, Kurth William, Lecoq Jean-Pierre, Bonhomme Vincent L
Department of Anesthesia and Intensive Care Medicine, Central University Hospital of Liege, Liege, Belgium
Department of Anesthesia and Intensive Care Medicine, Central University Hospital of Liege, Liege, Belgium.
Reg Anesth Pain Med. 2022 Jun 15. doi: 10.1136/rapm-2021-103427.
Posterolateral-approached total hip arthroplasty (PLTHA) is followed by moderate to severe postoperative pain. Suprainguinal fascia iliaca compartment block (SFICB) has been proposed as a promising analgesia technique.
Data from 86 patients scheduled for PLTHA with spinal anesthesia were analyzed in this prospective randomized controlled trial. Patients were randomly divided into two groups of 43 patients each. As opposed to the control group (group C), ropivacaine group (group R) received additional SFICB using 40 mL of 0.375% ropivacaine. As primary endpoint, blind observers noted total morphine consumption at postoperative 48 hours. Secondary endpoints were pain at rest and mobilization on 0-10 Numeric Rating Scale (rest and dynamic NRS) at fixed time points (1 hour and 6 hours after surgery, and at day 1 and day 2 at 8:00, 13:00 and 18:00 hours), walking performance at day 1 and day 2; postoperative complications including morphine-related side effects or orthostatic intolerance symptoms such as dizziness, nausea, blurred vision or vasovagal syncope.
A 48-hour morphine consumption (mg; median (IQR)) was significantly lower in group R than in group C (11 (8.5-15.5)) vs 26 (21-33.5), p<0001), as well as incidence of morphine-related side effects such as nausea at day 1 (p=0.04) and day 2 (p<0.01). Rest and dynamic NRS were globally significantly lower in group R than in group C (p<0.01). Group R showed less orthostatic intolerance at day 1 (p<0.001) and day 2 (p<0.01) and better functional walking performance at day 1 (<0.001) and day 2 (<0.001).
In PLTHA, SFICB provides opioid sparing, improved postoperative pain control, and enhanced functional recovery.
NCT04574479.
后外侧入路全髋关节置换术(PLTHA)术后会出现中度至重度疼痛。腹股沟上筋膜髂筋膜间隙阻滞(SFICB)被认为是一种有前景的镇痛技术。
在这项前瞻性随机对照试验中,分析了86例计划接受脊髓麻醉下PLTHA的患者的数据。患者被随机分为两组,每组43例。与对照组(C组)不同,罗哌卡因组(R组)额外接受了40毫升0.375%罗哌卡因的SFICB。作为主要终点,盲法观察者记录术后48小时的吗啡总消耗量。次要终点包括在固定时间点(术后1小时和6小时,以及第1天和第2天的8:00、13:00和18:00)使用0-10数字评分量表(静息和动态NRS)评估的静息和活动时疼痛、第1天和第2天的步行表现;术后并发症,包括吗啡相关副作用或体位性不耐受症状,如头晕、恶心、视力模糊或血管迷走性晕厥。
R组术后48小时吗啡消耗量(mg;中位数(IQR))显著低于C组(11(8.5-15.5)对26(21-33.5),p<0.001),以及第1天(p=0.04)和第2天(p<0.01)吗啡相关副作用如恶心的发生率。R组的静息和动态NRS总体上显著低于C组(p<0.01)。R组在第1天(p<0.001)和第2天(p<0.01)的体位性不耐受较少,在第1天(<0.001)和第2天(<0.001)的功能性步行表现更好。
在PLTHA中,SFICB可减少阿片类药物用量,改善术后疼痛控制,并促进功能恢复。
NCT04574479。