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SARS-CoV-2 在大流行早期的军队中的传播——系统分析。

SARS-CoV-2 Transmission in the Military during the Early Phase of the Pandemic-A Systematic Analysis.

机构信息

Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore 117549, Singapore.

Centre for Infectious Disease Epidemiology and Research, National University of Singapore, Singapore 117549, Singapore.

出版信息

Int J Environ Res Public Health. 2022 Jun 16;19(12):7418. doi: 10.3390/ijerph19127418.

Abstract

Militaries worldwide have been affected by COVID-19 pandemic. However, the impact and epidemiological characteristics of transmission during the early phase of the pandemic is not well-studied. This study aims to systematically estimate the baseline incidence of COVID-19 in the military worldwide and identify the potential risk factors of transmission and clinical characteristics of the cases. English and Chinese literature reporting COVID-19 cases in military worldwide published on four electronic databases (, and ) through 28 May 2021 were systematically screened and synthesized qualitatively. Forty-six studies involving at least 711,408 military personnel in 17 countries were synthesized. Low incidence of cases was observed in the military with pooled COVID-19 incidence of 0.19% (95%CI: 0.00-9.18%). We observed a higher incidence among those (1) with overseas exposure (39.85%; 95%CI: 0.00-95.87%) rather than local exposure (3.03%; 95%CI: 0.00-12.53%), (2) who were on either local/overseas military deployment (26.78%; 95%CI: 0.00-71.51%) as compared to those not deployed (4.37%; 95%CI: 0.00-17.93%), and (3) on overseas military deployment (39.84%; 95%CI: 0.00-95.87%) as compared to local military deployment (3.03%; 95%CI: 2.37-3.74%). The majority of the cases were symptomatic (77.90% (95%CI: 43.91-100.00%)); hospitalization and mortality rates were low at 4.43% (95%CI: 0.00-25.34%) and 0.25% (95%CI: 0.00-0.85%), respectively; and headache, anosmia, ageusia, myalgia, nasal congestion, and cough were the most commonly observed symptoms. Overseas and local deployment were observed to have higher risk of SARS-CoV-2 transmission. Sustainable, active SARS-CoV-2 surveillance strategies are crucial to detect and contain transmission early during military deployments.

摘要

全球各国军队均受到 COVID-19 大流行的影响。然而,大流行早期传播的影响和流行病学特征尚未得到充分研究。本研究旨在系统评估全球军队中 COVID-19 的基线发病率,并确定传播的潜在危险因素和病例的临床特征。通过四个电子数据库(PubMed、Embase、Web of Science 和 Cochrane Library),对截至 2021 年 5 月 28 日发表的全球军队中 COVID-19 病例的英文和中文文献进行系统筛选,并进行定性综合。综合了 17 个国家的 46 项至少纳入 711408 名军人的研究。军队中病例发生率较低,COVID-19 总发病率为 0.19%(95%CI:0.00-9.18%)。我们观察到,与本地暴露(3.03%,95%CI:0.00-12.53%)相比,有海外暴露(39.85%,95%CI:0.00-95.87%)的军人发病率更高;与未部署的军人(4.37%,95%CI:0.00-17.93%)相比,进行本地/海外军事部署的军人(26.78%,95%CI:0.00-71.51%)发病率更高;与进行本地军事部署的军人(3.03%,95%CI:2.37-3.74%)相比,进行海外军事部署的军人(39.84%,95%CI:0.00-95.87%)发病率更高。大多数病例为有症状的(77.90%(95%CI:43.91-100.00%));住院率和死亡率分别为 4.43%(95%CI:0.00-25.34%)和 0.25%(95%CI:0.00-0.85%),较低;最常见的症状是头痛、嗅觉丧失、味觉丧失、肌痛、鼻塞和咳嗽。海外和本地部署被观察到具有更高的 SARS-CoV-2 传播风险。可持续、积极的 SARS-CoV-2 监测策略对于在军事部署期间早期发现和控制传播至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d97b/9224230/130e9f8f7c61/ijerph-19-07418-g001.jpg

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