Abbamondi Gennaro Roberto, Tommonaro Giuseppina
Institute of Biomolecular Chemistry (ICB), National Research Council of Italy (CNR), Via Campi Flegrei 34, 80078 Pozzuoli, NA, Italy.
Microorganisms. 2022 Jun 10;10(6):1192. doi: 10.3390/microorganisms10061192.
Quorum sensing (QS) regulates the expression of several genes including motility, biofilm development, virulence expression, population density detection and plasmid conjugation. It is based on "autoinducers", small molecules that microorganisms produce and release in the extracellular milieu. The biochemistry of quorum sensing is widely discussed and numerous papers are available to scientists. The main purpose of this research is to understand how knowledge about this mechanism can be exploited for the benefit of humans and the environment. Here, we report the most promising studies on QS and their resulting applications in different fields of global interest: food, agriculture and nanomedicine.
群体感应(QS)调控包括运动性、生物膜形成、毒力表达、群体密度检测和质粒接合在内的多个基因的表达。它基于“自诱导物”,即微生物在细胞外环境中产生和释放的小分子。群体感应的生物化学已得到广泛讨论,科学家们可以获取大量相关论文。本研究的主要目的是了解如何利用有关该机制的知识造福人类和环境。在此,我们报告了关于群体感应最有前景的研究及其在全球关注的不同领域(食品、农业和纳米医学)中的应用成果。