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在印度尼西亚提供以医院为基础的(早期)抗逆转录病毒治疗的成本:近十年间有何变化?

The cost of providing hospital-based (early) antiretroviral treatment in Indonesia: what has changed in almost a decade?

作者信息

Vadra Jorghi, Komarudin Dindin, Prawiranegara Rozar, Lestari Mery, Wisaksana Rudi, Siregar Adiatma Y M

机构信息

Center for Economics and Development Studies (CEDS), Faculty of Economics and Business, Universitas Padjadjaran, Bandung, Indonesia.

HIV/AIDS Priority Setting Involving Stakeholder Using Multiple Criteria (PRISMA HIV), Universitas Padjadjaran, Bandung, Indonesia.

出版信息

AIDS Care. 2023 Jan;35(1):131-138. doi: 10.1080/09540121.2022.2113758. Epub 2022 Aug 25.

Abstract

17% of all people living with HIV in Indonesia who are in need of antiretroviral treatment (ART) actually receive the treatment. The cost of ART based on three CD4 cell count groups (e.g., 0-200, 201-350, >350 cells/mm) in a main referral hospital in West Java, Indonesia, in 2011-2016 was compared to the results from a decade earlier in the same setting. Costs were estimated including resources used for opportunistic infection treatment, laboratory tests, and antiretroviral (ARV) drugs. For each group, we divided the costs into several periods: pre-ART, and every 6 months up to 24 months after onset of treatment. Before ART, costs were dominated by laboratory tests (>80%); ARV drugs were the main cost after treatment onset (>92%). Average cost of treatment per year was US$600 across all groups. Moreover, the patient cost to access ART ( = 49 patients) did not exceed 10% of their household monthly expenditures (i.e., 4%). The unit cost of providing ART per patient/year is half the cost under the previous treatment initiation guidelines. A lower ARV drug cost, more patients in higher CD4 cell-count groups, and lower viral load test cost characterize the current cost profile.

摘要

在印度尼西亚,17% 需要抗逆转录病毒治疗(ART)的艾滋病毒感染者实际接受了治疗。将印度尼西亚西爪哇一家主要转诊医院2011 - 2016年基于三个CD4细胞计数组(例如,0 - 200、201 - 350、>350个细胞/mm)的ART成本与同一环境中十年前的结果进行了比较。成本估计包括用于机会性感染治疗、实验室检测和抗逆转录病毒(ARV)药物的资源。对于每个组,我们将成本分为几个阶段:ART前,以及治疗开始后每6个月直至24个月。在ART之前,成本主要由实验室检测主导(>80%);治疗开始后,ARV药物是主要成本(>92%)。所有组每年的平均治疗成本为600美元。此外,接受ART治疗的患者(n = 49例)的费用不超过其家庭月支出的10%(即4%)。每位患者每年提供ART的单位成本是先前治疗启动指南下成本的一半。较低的ARV药物成本、较高CD4细胞计数组中更多的患者以及较低的病毒载量检测成本是当前成本概况的特征。

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