Horgan Denis, Führer-Sakel Dagmar, Soares Paula, Alvarez Clara V, Fugazzola Laura, Netea-Maier Romana T, Jarzab Barbara, Kozaric Marta, Bartes Beate, Schuster-Bruce James, Dal Maso Luigino, Schlumberger Martin, Pacini Furio
European Alliance for Personalised Medicine, 1040 Brussels, Belgium.
Department of Endocrinology, Diabetes and Metabolism, Endocrine Tumour Center at West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, 45122 Duisburg, Germany.
Healthcare (Basel). 2022 Aug 25;10(9):1621. doi: 10.3390/healthcare10091621.
Thyroid cancer (TC) is the most common malignancy of the endocrine system that affects the thyroid gland. It is usually treatable and, in most cases, curable. The central issues are how to improve knowledge on TC, to accurately identify cases at an early stage that can benefit from effective intervention, optimise therapy, and reduce the risk of overdiagnosis and unnecessary treatment. Questions remain about management, about treating all patients in referral centres, and about which treatment should be proposed to any individual patient and how this can be optimised. The European Alliance for Personalised Medicine (EAPM) hosted an expert panel discussion to elucidate some of the challenges, and to identify possible steps towards effective responses at the EU and member state level, particularly in the context of the opportunities in the European Union's evolving initiatives-notably its Beating Cancer Plan, its Cancer Mission, and its research funding programmes. Recommendations emerging from the panel focus on improved infrastructure and funding, and on promoting multi-stakeholder collaboration between national and European initiatives to complement, support, and mutually reinforce efforts to improve patient care.
甲状腺癌(TC)是影响甲状腺的最常见内分泌系统恶性肿瘤。它通常是可治疗的,而且在大多数情况下是可治愈的。核心问题在于如何增进对甲状腺癌的了解,如何准确早期识别可从有效干预中获益的病例,优化治疗,并降低过度诊断和不必要治疗的风险。关于管理、在转诊中心治疗所有患者、应向任何个体患者推荐何种治疗以及如何优化治疗等问题仍然存在。欧洲个性化医疗联盟(EAPM)举办了一次专家小组讨论,以阐明其中一些挑战,并确定在欧盟和成员国层面采取有效应对措施的可能步骤,特别是在欧盟不断发展的倡议所带来的机遇背景下——尤其是其《战胜癌症计划》、《癌症使命》及其研究资助计划。专家小组提出的建议侧重于改善基础设施和资金,并促进国家和欧洲倡议之间的多利益相关方合作,以补充、支持和相互加强改善患者护理的努力。