Paracelsus Medical University, Salzburg, Austria.
Division of Clinical Microbiology, Mayo Clinic, Rochester, Minnesota, USA.
Antimicrob Agents Chemother. 2023 Jan 24;67(1):e0116622. doi: 10.1128/aac.01166-22. Epub 2022 Dec 6.
The antibiofilm activity of a hypochlorous acid (HOCl)-producing electrochemical bandage (e-bandage) was assessed against 14 yeast isolates . The evaluated e-bandage was polarized at +1.5 V to allow continuous production of HOCl. Time-dependent decreases in the biofilm CFU counts were observed for all isolates with e-bandage treatment. The results suggest that the described HOCl-producing e-bandage could serve as a potential alternative to traditional antifungal wound biofilm treatments.
一种次氯酸(HOCl)产生电化学绷带(e 绷带)的抗生物膜活性被评估了对 14 株酵母分离物的作用。评估的 e 绷带被极化在 +1.5V 以允许 HOCl 的连续产生。用 e 绷带处理时,所有分离物的生物膜 CFU 计数都观察到了时间依赖性的减少。结果表明,所描述的产生 HOCl 的 e 绷带可以作为传统抗真菌伤口生物膜治疗的潜在替代物。