薰衣草花序的植物化学剖析：酚类物质的宝贵且有前景的资源

Phytoprofiling of L. Inflorescences: A Valuable and Promising Resource for Phenolics.

作者信息

Zymone Kristina, Raudone Lina, Žvikas Vaidotas, Jakštas Valdas, Janulis Valdimaras

机构信息

Department of Analytical and Toxicological Chemistry, Lithuanian University of Health Sciences, Sukileliu Av. 13, LT-50162 Kaunas, Lithuania.

Laboratory of Biopharmaceutical Research, Institute of Pharmaceutical Technologies, Lithuanian University of Health Sciences, Sukileliu Av. 13, LT-50162 Kaunas, Lithuania.

出版信息

Plants (Basel). 2022 Dec 7;11(24):3421. doi: 10.3390/plants11243421.

DOI:10.3390/plants11243421

PMID:36559532

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9780963/

Abstract

The leaves and fruits of various L. genotypes have long ethnopharmacological and food-usage histories, but inflorescences are still underutilized and neglected materials with scarce phytochemical scientific evidence. The aim of this study was to determine the phenolic profiles of inflorescence extracts of 26 species, genotypes, and cultivars. HPLC and UPLS with MS detection were applied, and coupled data revealed unique phytochemical phenolic profiles. Neochlorogenic and chlorogenic acids were the key compounds, reaching up to 5.8 mg/g of dw. Rutin, isoquercitrin, quercetin 3malonylglucoside, isorhamnetin 3rutinoside, sexangularetin derivative, and kaempferol acetyl hexoside were detected in all inflorescence samples. Overall, high quantitative heterogeneity across the various genotypes was found by profiling. Phenolic fingerprint profiles and sexangularetin derivatives could serve as markers in authenticity studies and quality control schemes. The species , , , and and the cultivars 'Chamsis Louing', 'Coral Beauty', and 'Edulis' could be used as target genotypes for production of smart and innovative inflorescence matrix-based ingredients.

摘要

不同枸杞基因型的叶子和果实有着悠久的民族药理学应用和食用历史，但花序仍是未得到充分利用且被忽视的材料，关于其植物化学的科学证据稀缺。本研究的目的是确定26个物种、基因型和栽培品种的花序提取物中的酚类成分。采用了配有质谱检测的高效液相色谱法（HPLC）和超高效液相色谱法（UPLS），相关联的数据揭示了独特的植物化学酚类成分。新绿原酸和绿原酸是关键化合物，含量高达5.8毫克/克干重。在所有花序样品中均检测到了芦丁、异槲皮苷、槲皮素3 - 丙二酰葡萄糖苷、异鼠李素3 - 芸香糖苷、六棱菊素衍生物和山奈酚乙酰己糖苷。总体而言，通过分析发现不同基因型之间存在高度的定量异质性。酚类指纹图谱和六棱菊素衍生物可作为鉴定研究和质量控制方案中的标志物。枸杞属的某些物种以及‘Chamsis Louing’‘Coral Beauty’和‘Edulis’等栽培品种可作为生产基于智能创新花序基质成分的目标基因型。