韩国与 2019 年冠状病毒病（COVID-19）相关的儿科死亡病例。

Pediatric Deaths Associated With Coronavirus Disease 2019 (COVID-19) in Korea.

机构信息

Data Analysis Team, Epidemiological Investigation and Analysis Task Force, Central Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Korea.

Department of Pediatrics, Korea University Anam Hospital, Seoul, Korea.

出版信息

J Korean Med Sci. 2023 Jan 16;38(3):e21. doi: 10.3346/jkms.2023.38.e21.

DOI:10.3346/jkms.2023.38.e21

PMID:36647219

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9842489/

Abstract

As of September 3, 2022, 5,388,338 coronavirus disease 2019 (COVID-19) cases and 46 deaths (3 in 2021 and 43 in 2022) were reported in children ≤ 18 years in Korea. Cumulative confirmed cases accounted for 67.3% of the population aged ≤ 18 years and case fatality rate was 0.85/100,000. Among 46 fatal cases, 58.7% were male and median age was 7 years. Underlying diseases were present in 47.8%; neurologic diseases (63.6%) and malignancy (13.6%) most common. Only four had history of COVID-19 immunization. COVID-19 associated deaths occurred at median 2 days from diagnosis (range: -1 to 21). Among COVID-19 deaths, 41.3% occurred before admission; 2 before hospital arrival and 17 in the emergency department. Among children whose cause was documented, myocarditis, respiratory and multiorgan failure were most common. COVID-19 associated death was seen early after diagnosis in children and public health policies to provide access to medical care for children with COVID-19 are essential during the pandemic.

摘要

截至 2022 年 9 月 3 日，韩国报告了 5388338 例 2019 年冠状病毒病（COVID-19）病例和 46 例死亡病例（2021 年 3 例，2022 年 43 例），涉及≤18 岁的儿童。累计确诊病例占≤18 岁人群的 67.3%，病死率为 0.85/10 万。在 46 例死亡病例中，男性占 58.7%，中位年龄为 7 岁。有基础疾病的占 47.8%；最常见的是神经系统疾病（63.6%）和恶性肿瘤（13.6%）。仅有 4 例有 COVID-19 免疫接种史。COVID-19 相关死亡发生在诊断后的中位时间为 2 天（范围：-1 至 21）。在 COVID-19 死亡病例中，41.3%发生在入院前；2 例在医院到达前，17 例在急诊科。在有记录病因的儿童中，心肌炎、呼吸和多器官衰竭最常见。COVID-19 相关死亡在儿童诊断后早期发生，大流行期间为儿童提供获得 COVID-19 医疗服务的公共卫生政策至关重要。