Manner Hendrik
Dtsch Med Wochenschr. 2023 Feb;148(3):93-102. doi: 10.1055/a-1832-3984. Epub 2023 Jan 23.
Barrett's esophagus has been an important issue in clinical medicine for many years. In the 70 s of the last century, the association between gastroesophageal reflux disease and BE was detected. Only ten years later, the association between BE and adenocarcinoma of the esophagus was reported. Starting in the 90s in Europe, endoscopic resection and ablation have seen an expanding role in the management of BE. In analogy with other diseases, patients are undergoing individualized surveillance and treatment strategies. In non-neoplastic Barrett's esophagus, surveillance intervals are clearly defined by national and European guidelines. Only in case of malignant transformation of BE which may range from low-grade dysplasia to high-grade dysplasia and early Barrett's cancer, endoscopic therapy is indicated. At present, there are emerging techniques of artificial intelligence. Due to these rapid developments in BE management, it is important to keep an eye on the current status of BE management.
多年来,巴雷特食管一直是临床医学中的一个重要问题。上世纪70年代,人们发现了胃食管反流病与巴雷特食管之间的关联。仅仅十年后,就有报道称巴雷特食管与食管腺癌之间存在关联。从20世纪90年代起在欧洲,内镜切除和消融在巴雷特食管的治疗中发挥着越来越重要的作用。与其他疾病类似,患者正在接受个体化的监测和治疗策略。在非肿瘤性巴雷特食管中,国家和欧洲指南明确规定了监测间隔。只有在巴雷特食管发生恶性转化(范围可能从低度异型增生到高度异型增生以及早期巴雷特癌)的情况下,才需要进行内镜治疗。目前,人工智能技术不断涌现。由于巴雷特食管治疗方面的这些快速发展,密切关注巴雷特食管治疗的现状非常重要。