Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA.
Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, California, USA.
Neurosurgery. 2023 Mar 1;92(3):490-496. doi: 10.1227/neu.0000000000002227. Epub 2022 Nov 16.
As the opioid epidemic accelerates in the United States, numerous sociodemographic factors have been implicated its development and are, furthermore, a driving factor of the disparities in postoperative pain management. Recent studies have suggested potential associations between the influence of race and ethnicity on pain perception but also the presence of unconscious biases in the treatment of pain in minority patients.
To characterize the perioperative opioid requirements across racial groups after spine surgery.
A retrospective, observational study of 1944 opioid-naive adult patients undergoing a neurosurgical spine procedure, from June 2012 to December 2019, was performed at a large, quaternary care institute. Postoperative inpatient and outpatient opioid usage was measured by oral morphine equivalents, across various racial groups.
Case characteristics were similar between racial groups. In the postoperative period, White patients had shorter lengths of stay compared with Black and Asian patients ( P < .05). Asian patients used lower postoperative inpatient opioid doses in comparison with White patients ( P < .001). White patients were discharged with significantly higher doses of opioids compared with Black patients ( P < .01); however, they were less likely to be readmitted within 30 days of discharge ( P < .01).
In a large cohort of opioid-naive postoperative neurosurgical patients, this study demonstrates higher inpatient and outpatient postoperative opioid usage among White patients. Increasing physician awareness to the effect of race on inpatient and outpatient pain management would allow for a modified opioid prescribing practice that ensures limited yet effective opioid dosages void of implicit biases.
在美国,阿片类药物泛滥的情况正在加速,许多社会人口因素与其发展有关,并且是导致术后疼痛管理差异的一个驱动因素。最近的研究表明,种族对疼痛感知的影响以及少数族裔患者治疗疼痛时存在无意识偏见之间可能存在关联。
描述脊柱手术后不同种族群体的围手术期阿片类药物需求。
对 2012 年 6 月至 2019 年 12 月在一家大型四级医疗机构接受神经外科脊柱手术的 1944 名阿片类药物初治成年患者进行了回顾性、观察性研究。通过口服吗啡当量测量了不同种族群体的术后住院和门诊阿片类药物使用情况。
种族群体之间的病例特征相似。在术后期间,与黑人和亚洲患者相比,白人患者的住院时间更短(P <.05)。与白人患者相比,亚洲患者术后住院期间使用的阿片类药物剂量较低(P <.001)。与黑人患者相比,白人患者出院时携带的阿片类药物剂量明显更高(P <.01);然而,他们在出院后 30 天内再次入院的可能性较低(P <.01)。
在一个大型的阿片类药物初治术后神经外科患者队列中,本研究表明白人患者的住院和门诊术后阿片类药物使用量较高。提高医生对种族对住院和门诊疼痛管理影响的认识,将有助于修改阿片类药物的处方实践,确保剂量有限但有效的阿片类药物,避免无意识偏见。