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对乳上颌磨牙进行牙髓摘除术后立即使用对乙酰氨基酚和布洛芬对牙髓麻醉的影响

Effects of Acetaminophen and Ibuprofen on Pulpal Anaesthesia Immediately after Pulpectomy of Primary Maxillary Molars.

作者信息

Bahrololoomi Zahra, Amrollahi Narjes

机构信息

Department of Pediatric Dentistry, School of Dentistry, Social Determinants of Oral Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Dental Research Center, Department of Pediatric Dentistry, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Iran Endod J. 2019 Spring;14(2):104-109. doi: 10.22037/iej.v14i2.22799.

Abstract

INTRODUCTION

This study aimed to evaluate the effects of acetaminophen and ibuprofen on pulpal anaesthesia immediately after pulpectomy of primary maxillary molars.

METHODS AND MATERIALS

In this placebo-controlled, double-blind clinical trial, 60 children (aged 5 to 9) were referred to the Department of Pediatric Dentistry, Yazd Dental School; for primary maxillary molar pulpectomy. Local anaesthesia and analgesic drugs were used for the pre-operative stage. A five-face scale was considered to evaluate pain reaction during the pulp therapy. Pain scores were determined when the dental procedure was complete. The Kruskal-Wallis and Mann-Whitney U tests were finally used at the confidence level of 95%.

RESULTS

Use of analgesics before pulpectomy in children can reduce pain score compared to placebo group (<0.001) and increase the effectiveness of pulpal anesthesia. Additionally, ibuprofen exhibited lower pain scores compared to acetaminophen although the difference was not statistically significant.

CONCLUSIONS

Pre-operative use of ibuprofen and acetaminophen might be a useful way to achieve analgesia during pulpectomy of primary maxillary molars in children.

摘要

引言

本研究旨在评估对乳牙上颌第一磨牙进行牙髓摘除术后立即使用对乙酰氨基酚和布洛芬对牙髓麻醉的效果。

方法与材料

在这项安慰剂对照的双盲临床试验中,60名5至9岁的儿童被转诊至亚兹德牙科学院儿童牙科;接受乳牙上颌第一磨牙牙髓摘除术。术前阶段使用了局部麻醉药和镇痛药。采用五面部量表评估牙髓治疗期间的疼痛反应。在牙科手术完成时确定疼痛评分。最终在95%的置信水平下使用Kruskal-Wallis检验和Mann-Whitney U检验。

结果

与安慰剂组相比,儿童牙髓摘除术前使用镇痛药可降低疼痛评分(<0.001),并提高牙髓麻醉的效果。此外,与对乙酰氨基酚相比,布洛芬的疼痛评分更低,尽管差异无统计学意义。

结论

术前使用布洛芬和对乙酰氨基酚可能是在儿童乳牙上颌第一磨牙牙髓摘除术中实现镇痛的一种有用方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5877/9968387/4461133e7ceb/IEJ-14-104-g001.jpg

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