Suppr超能文献

急性肠系膜缺血的管理:一项全球调查的结果。

Management of acute mesenteric ischaemia: Results of a worldwide survey.

作者信息

Hess Benjamin, Cahenzli Martin, Forbes Alastair, Burgos Rosa, Coccolini Federico, Corcos Olivier, Holst Mette, Irtun Øivind, Klek Stanislaw, Pironi Loris, Rasmussen Henrik Højgaard, Serlie Mireille J, Thibault Ronan, Gabe Simon, Reintam Blaser Annika

机构信息

Department of Intensive Care Medicine, Lucerne Cantonal Hospital, Lucerne, Switzerland.

Department of Intensive Care Medicine, Lucerne Cantonal Hospital, Lucerne, Switzerland.

出版信息

Clin Nutr ESPEN. 2023 Apr;54:194-205. doi: 10.1016/j.clnesp.2022.12.022. Epub 2023 Jan 5.

Abstract

BACKGROUND

Acute mesenteric ischaemia (AMI) is a condition with high mortality. This survey assesses current attitudes and practices to manage AMI worldwide.

METHODS

A questionnaire survey about the practices of diagnosing and managing AMI, endorsed by several specialist societies, was sent to different medical specialists and hospitals worldwide. Data from individual health care professionals and from medical teams were collected.

RESULTS

We collected 493 individual forms from 71 countries and 94 team forms from 34 countries. Almost half of respondents were surgeons, and most of the responding teams (70%) were led by surgeons. Most of the respondents indicated that diagnosis of AMI is often delayed but rarely missed. Emergency revascularisation is often considered for patients with AMI but rarely in cases of transmural ischaemia (intestinal infarction). Responses from team hospitals with a dedicated special unit (14 team forms) indicated more aggressive revascularisation. Abdominopelvic CT-scan with intravenous contrast was suggested as the most useful diagnostic test, indicated by approximately 90% of respondents. Medical history and risk factors were thought to be more important in diagnosis of AMI without transmural ischaemia, whereas for intestinal infarction, plasma lactate concentrations and surgical exploration were considered more useful. In elderly patients, a palliative approach is often chosen over extensive bowel resection. There was a large variability in anticoagulant treatment, as well as in timing of surgery to restore bowel continuity.

CONCLUSIONS

Delayed diagnosis of AMI is common despite wide availability of an adequate imaging modality, i.e. CT-scan. Large variability in treatment approaches exists, indicating the need for updated guidelines. Increased awareness and knowledge of AMI may improve current practice until more robust evidence becomes available. Adherence to the existing guidelines may help in improving differences in treatment and outcomes.

摘要

背景

急性肠系膜缺血(AMI)是一种死亡率很高的疾病。本调查评估了全球范围内对AMI的当前管理态度和实践。

方法

一份由多个专科协会认可的关于AMI诊断和管理实践的问卷调查表被发送给全球不同的医学专家和医院。收集了来自个体医疗保健专业人员和医疗团队的数据。

结果

我们从71个国家收集了493份个体表格,从34个国家收集了94份团队表格。近一半的受访者是外科医生,大多数应答团队(70%)由外科医生领导。大多数受访者表示,AMI的诊断经常延迟,但很少漏诊。AMI患者常考虑进行紧急血运重建,但透壁缺血(肠梗死)的情况很少进行。设有专门特殊科室的团队医院(14份团队表格)的回复表明血运重建更为积极。约90%的受访者认为静脉造影剂增强的腹盆腔CT扫描是最有用的诊断检查。病史和危险因素在无透壁缺血的AMI诊断中被认为更为重要,而对于肠梗死,血浆乳酸浓度和手术探查被认为更有用。在老年患者中,通常选择姑息治疗而非广泛的肠切除术。抗凝治疗以及恢复肠连续性的手术时机差异很大。

结论

尽管有足够的成像方式(即CT扫描)广泛可用,但AMI的诊断延迟仍然很常见。治疗方法存在很大差异,表明需要更新指南。在获得更有力的证据之前,提高对AMI的认识和了解可能会改善当前的实践。遵循现有指南可能有助于改善治疗和结果的差异。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验