天津市农村中老年人群膝关节骨关节炎的患病率及相关因素：一项基于人群的横断面研究。
Prevalence and factors associated with knee osteoarthritis among middle-aged and elderly individuals in rural Tianjin: a population-based cross-sectional study.
机构信息
Department of Orthopedics, Tianjin Jizhou Hospital of Traditional Chinese Medicine, Tianjin, 301900, China.
Department of Pharmacy, Tianjin Jizhou People's Hospital, Tianjin, 301900, China.
出版信息
J Orthop Surg Res. 2023 Apr 1;18(1):266. doi: 10.1186/s13018-023-03742-4.
BACKGROUND
The prevalence of osteoarthritis has been investigated in many countries and regions. Considering the wide differences in ethnicity, socioeconomic status, environmental factors, and lifestyle patterns, our study aimed to report the prevalence of knee osteoarthritis (KOA) and its associated factors in rural areas of Tianjin.
METHODS
This population-based cross-sectional study was conducted between June and August 2020. KOA was diagnosed according to the 1995 American College of Rheumatology criteria. Information on participants' age, years of education, BMI, smoking and drinking status, sleep quality, and frequency of walking were collected. Multivariate logistic regression analysis was used to analyze factors influencing KOA.
RESULTS
This study included 3924 participants (1950 male and 1974 female); the mean age of all participants was 58.53 years. In total, 404 patients were diagnosed with KOA, and the overall prevalence of KOA was 10.3%. The prevalence of KOA was higher in women than in men (14.1% vs. 6.5%). The risk of KOA in women was 1.764 times higher than that in men. The risk of KOA increased following the increasement of age. There was higher risk of KOA in participants who walked frequently than in participants who walked infrequently (OR = 1.572); in participants with overweight than in participants with normal weight (OR = 1.509), in participants with average sleep quality (OR = 1.677) and those with perceived poor sleep quality (OR = 1.978), respectively, than participants with satisfactory sleep quality, and in postmenopausal women than in non-menopausal women (OR = 4.12). The risk of KOA in participants with an elementary level was lower (0.619 times) than participants with illiteracy. In addition, the results of gender subgroup analysis showed that in male, age, obesity, frequent walking and sleep quality were independent factors associated with KOA; while in female, age, BMI, education level, sleep quality, frequent walking and whether menopausal were independent factors associated with KOA (P < 0.05).
CONCLUSION
The results of our population-based cross-sectional study showed that sex, age, educational level, BMI, sleep quality, and frequent walking were independent influencing factors for KOA, and the influencing factors for KOA differed between the sexes. In order to reduce the disease burden of KOA and the harm to the health of middle-aged and elderly people, the risk factors related to the control of KOA should be identified as much as possible.
TRIAL REGISTRATION
ChiCTR2100050140.
背景
骨关节炎的患病率已在许多国家和地区进行了调查。考虑到种族、社会经济地位、环境因素和生活方式的广泛差异，我们的研究旨在报告天津市农村地区膝骨关节炎（KOA）的患病率及其相关因素。
方法
本研究为基于人群的横断面研究，于 2020 年 6 月至 8 月进行。根据 1995 年美国风湿病学会标准诊断 KOA。收集参与者的年龄、受教育年限、BMI、吸烟和饮酒状况、睡眠质量和步行频率等信息。采用多变量逻辑回归分析影响 KOA 的因素。
结果
本研究共纳入 3924 名参与者（男 1950 名，女 1974 名）；所有参与者的平均年龄为 58.53 岁。共有 404 名患者被诊断为 KOA，KOA 的总患病率为 10.3%。女性 KOA 的患病率高于男性（14.1%比 6.5%）。女性患 KOA 的风险是男性的 1.764 倍。随着年龄的增长，KOA 的风险增加。与步行频率低的参与者相比，步行频率高的参与者 KOA 的风险更高（OR=1.572）；与体重正常的参与者相比，超重的参与者（OR=1.509）、平均睡眠质量（OR=1.677）和睡眠质量差（OR=1.978）的参与者、与睡眠质量满意的参与者相比，绝经后的女性患 KOA 的风险更高（OR=4.12）。与文盲相比，文化程度为小学的参与者患 KOA 的风险较低（0.619 倍）。此外，性别亚组分析结果表明，在男性中，年龄、肥胖、频繁行走和睡眠质量是与 KOA 相关的独立因素；而在女性中，年龄、BMI、教育水平、睡眠质量、频繁行走和是否绝经是与 KOA 相关的独立因素（P<0.05）。
结论
本基于人群的横断面研究结果表明，性别、年龄、教育水平、BMI、睡眠质量和行走频率是 KOA 的独立影响因素，且 KOA 的影响因素在性别间存在差异。为了降低 KOA 的疾病负担和对中老年人健康的危害，应尽可能识别与 KOA 控制相关的危险因素。
试验注册
ChiCTR2100050140。
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