双酚A对糖尿病及其慢性并发症的潜在影响：一篇叙述性综述。
Potential effects of bisphenol A on diabetes mellitus and its chronic complications: A narrative review.
作者信息
Jiang Wei, Ding Kaixi, Huang Wenjie, Xu Feng, Lei Ming, Yue Rensong
机构信息
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Chengdu University of Technology, College of Ecology and Environment, Chengdu, 610075, China.
出版信息
Heliyon. 2023 May 17;9(5):e16340. doi: 10.1016/j.heliyon.2023.e16340. eCollection 2023 May.
Diabetes mellitus (DM) is a metabolic disease caused by multiple factors such as genetics, environment, and lifestyle. Bisphenol A (BPA), as one of the most common endocrine-disrupting chemicals (EDCs), has been strongly implicated in the development of type 2 diabetes mellitus (T2DM). BPA exposure is associated with target organ damage in DM and may exacerbate the progression of some chronic complications of DM. This paper reviews relevant epidemiological, in vivo, and in vitro studies to better understand BPA's potential risk associations and pathological mechanisms in several chronic diabetic complications.
糖尿病（DM）是一种由遗传、环境和生活方式等多种因素引起的代谢性疾病。双酚A（BPA）作为最常见的内分泌干扰化学物质（EDCs）之一，与2型糖尿病（T2DM）的发生密切相关。接触BPA与糖尿病中的靶器官损伤有关，可能会加剧糖尿病一些慢性并发症的进展。本文综述了相关的流行病学、体内和体外研究，以更好地了解BPA在几种慢性糖尿病并发症中的潜在风险关联和病理机制。
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