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中国和全球 COPD 负担:2019 年全球疾病负担研究的系统分析。

Burden of COPD in China and the global from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019.

机构信息

School of Public Health, Dalian Medical University, Dalian, Liaoning, China.

Department of Health Policy and Management, Peking University, Beijing, China.

出版信息

BMJ Open Respir Res. 2023 Jul;10(1). doi: 10.1136/bmjresp-2023-001698.

Abstract

OBJECTIVE

To investigate the current disease burden of chronic obstructive pulmonary disease (COPD) in China and globally using the Global Burden of Disease (GBD) data in 2019, as well as to analyse the changes in its risk factors, providing a scientific basis for the formulation of a comprehensive prevention and control strategy for COPD in China.

STUDY DESIGN

An observational study based on the GBDs.

METHODS

Based on the GBD 2019 database, we obtained data on incidence, prevalence, mortality, disability-adjusted life years (DALYs) and corresponding age-standardised rates of COPD in China and the global, and analysed and described the changing trends of COPD burden in China and the global from 1990 to 2019.

RESULTS

In 2019, the total number of COPD deaths in China was 1.04 (95% uncertainty intervals (95% UI): 0.89-1.27) million cases, the number of patients with COPD was 45.16 (95% UI: 41.13-49.62) million cases, and the number of new cases was 4.0 (95% UI: 3.6-4.4) million cases. DALYs were 74.4 (95% UI: 68.2-80.2) million years. Compared with 1990, the number of new incident cases and the overall prevalence of COPD in China in 2019 increased by 66.20% and 66.76%, respectively, which is lower than the overall global level.

CONCLUSION

From 1990 to 2019, the age-standardized prevalence rate (ASPR), the age-standardized incidence rate (ASIR) and the age-standardized death rate (ASDR) in China and the global all showed a downward trend, and the rate of decline in China was much higher than the overall level of the world, indicating that China has made specific achievements in the prevention and treatment of COPD, but overall the disease burden of COPD is still hefty, and the number of affected individuals is still increasing.

摘要

目的

利用 2019 年全球疾病负担(GBD)数据,研究中国和全球慢性阻塞性肺疾病(COPD)的当前疾病负担,并分析其危险因素的变化,为中国制定全面的 COPD 防控策略提供科学依据。

研究设计

基于 GBD 的观察性研究。

方法

基于 GBD 2019 数据库,我们获得了中国和全球 COPD 的发病率、患病率、死亡率、伤残调整生命年(DALYs)和相应的年龄标准化率的数据,并分析和描述了 1990 年至 2019 年中国和全球 COPD 负担的变化趋势。

结果

2019 年,中国 COPD 总死亡人数为 104 万(95%不确定区间[95%UI]:0.89-1.27)例,COPD 患者人数为 4516 万(95%UI:4113-4962)例,新发病例数为 400 万(95%UI:3.6-4.4)例。DALYs 为 7440 万(95%UI:6820-8020)年。与 1990 年相比,2019 年中国新发病例数和总体 COPD 患病率分别增加了 66.20%和 66.76%,低于全球总体水平。

结论

1990 年至 2019 年,中国和全球的年龄标准化患病率(ASPR)、年龄标准化发病率(ASIR)和年龄标准化死亡率(ASDR)均呈下降趋势,且中国的下降速度明显高于全球水平,表明中国在 COPD 的防治方面取得了具体成效,但总体而言,COPD 的疾病负担仍然较重,受影响人群的数量仍在增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c89/10347506/aee3b904684e/bmjresp-2023-001698f01.jpg

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