Shor Samuel M, Schweig Sunjya K
Internal Medicine of Northern Virginia, George Washington University Health Care Sciences, Reston, VA 20190, USA.
California Center for Functional Medicine, Oakland, CA 94619, USA.
Microorganisms. 2023 Jul 5;11(7):1759. doi: 10.3390/microorganisms11071759.
The primary objective of this paper is to provide an evidence-based update of the literature on the use of bioactive phytochemicals, nutraceuticals, and micronutrients (dietary supplements that provide health benefits beyond their nutritional value) in the management of persistent cases of infection (Lyme disease) and two other tick-borne pathogens, and species. Recent studies have advanced our understanding of the pathophysiology and mechanisms of persistent infections. These advances have increasingly enabled clinicians and patients to utilize a wider set of options to manage these frequently disabling conditions. This broader toolkit holds the promise of simultaneously improving treatment outcomes and helping to decrease our reliance on the long-term use of pharmaceutical antimicrobials and antibiotics in the treatment of tick-borne pathogens such as , , and .
本文的主要目的是提供一份基于证据的文献更新,内容涉及生物活性植物化学物质、营养保健品和微量营养素(具有超出其营养价值的健康益处的膳食补充剂)在持续性感染(莱姆病)以及另外两种蜱传病原体和物种的管理中的应用。最近的研究增进了我们对持续性感染的病理生理学和机制的理解。这些进展使临床医生和患者越来越能够利用更广泛的选择来管理这些常常使人衰弱的病症。这个更广泛的工具包有望同时改善治疗效果,并有助于减少我们在治疗蜱传病原体(如、和)时对长期使用药物抗菌剂和抗生素的依赖。