Ruan Hanguang, Okamoto Masahiko, Ohno Tatsuya, Li Yang, Zhou Yuan
Department of Radiation Oncology, Gunma University, Maebashi, Japan.
Gunma University Heavy Ion Medical Center, Gunma University, Maebashi, Gunma, Japan.
Front Oncol. 2023 Aug 16;13:1107703. doi: 10.3389/fonc.2023.1107703. eCollection 2023.
Breast cancer is the most common malignant tumor in female patients. Along with surgery, radiotherapy is one of the most commonly prescribed treatments for breast cancer. Over the past few decades, breast cancer radiotherapy technology has significantly improved. Nevertheless, related posttherapy complications should not be overlooked. Common complications include dose-related coronary toxicity, radiation pneumonia, and the risk of second primary cancer of the contralateral breast. Particle radiotherapy with protons or carbon ions is widely attracting interest as a potential competitor to conventional photon radiotherapy because of its superior physical and biological characteristics. This article summarizes the results of clinical research on proton and carbon-ion radiotherapy for treating breast cancer.
乳腺癌是女性患者中最常见的恶性肿瘤。与手术一样,放射治疗是乳腺癌最常用的治疗方法之一。在过去几十年中,乳腺癌放射治疗技术有了显著改进。然而,相关的治疗后并发症不容忽视。常见并发症包括与剂量相关的冠状动脉毒性、放射性肺炎以及对侧乳腺发生第二原发性癌症的风险。由于质子或碳离子粒子放疗具有优越的物理和生物学特性,作为传统光子放疗的潜在竞争对手,它正广泛吸引着人们的关注。本文总结了质子和碳离子放疗治疗乳腺癌的临床研究结果。