Clinical Medical College, Yangzhou University, Yangzhou, China.
Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Tissue Eng Part B Rev. 2024 Apr;30(2):198-216. doi: 10.1089/ten.TEB.2023.0129. Epub 2023 Sep 28.
The development of tracheal tissue engineering (TTE) has seen a rapid growth in recent years. The purpose of this study was to investigate the global status, trends, and hotspots of TTE research based on bibliometrics and visualization analysis. Publications related to TTE were retrieved and included in the Web of Science Core Collection. VOSviewer and CiteSpace were used to generate knowledge maps. Six hundred fifty-five publications were identified, and the quantity of the annual publications worldwide was on the increase. International collaboration is a widespread reality. The United States led the world in the field of trachea tissue engineering, whereas University College London was the institution with the greatest contribution. In addition, had a great influence in this field, attracting the largest number of papers. Moreover, the topics of TTE research largely concentrated on the biomechanical scaffold preparation, the vascularization and epithelialization of scaffold, the tracheal cartilage regeneration, and the tissue-engineered tracheal transplantation. And the research on the application of decellularization and 3D printing for the construction of a tissue-engineered trachea was likely to receive more widespread attention in the future. Impact statement In recent years, tracheal tissue engineering (TTE) has experienced rapid growth. In this study, we investigated the worldwide status and trends of TTE research, and revealed the countries, institutions, journals, and authors that had made significant contributions to the field of TTE. Moreover, the possible research hotspots in the future were predicted. According to our research, researchers can gain a better understanding of the trends in this field, and stay informed of the most current research by tracking key journals, institutions, and authors.
近年来,气管组织工程(TTE)发展迅速。本研究旨在通过文献计量学和可视化分析,调查 TTE 研究的全球现状、趋势和热点。检索与 TTE 相关的出版物,并将其纳入 Web of Science 核心合集。使用 VOSviewer 和 CiteSpace 生成知识图谱。共确定了 655 篇出版物,全球年度出版物数量呈上升趋势。国际合作是普遍存在的现实。美国在气管组织工程领域处于领先地位,而伦敦大学学院是贡献最大的机构。此外,[杂志名称]在该领域具有很大的影响力,吸引了最多的论文。此外,TTE 研究的主题主要集中在生物力学支架的制备、支架的血管化和上皮化、气管软骨再生以及组织工程气管移植上。未来,脱细胞和 3D 打印在构建组织工程气管方面的应用研究可能会受到更广泛的关注。