Ministry of Health, Riyadh, Saudi Arabia.
GSK, Jeddah, Saudi Arabia.
Hum Vaccin Immunother. 2023 Aug 1;19(2):2253585. doi: 10.1080/21645515.2023.2253585.
Pertussis is a serious and potentially fatal disease in infants too young for vaccination. Despite a high vaccine coverage in children, pertussis continues to occur in unvaccinated infants in the Kingdom of Saudi Arabia (KSA). Available data supports the use of maternal pertussis immunization for preventing pertussis in young infants. In June 2019, the Saudi Ministry of Health recommended maternal pertussis immunization with combined tetanus-diphtheria-acellular pertussis vaccine (Tdap) during every pregnancy. To understand barriers to maternal immunization and identify strategies to improve maternal immunization, we conducted an online survey in November and December 2020, asking 60 obstetricians/gynecologists about their attitudes to maternal pertussis immunization. Fewer than 50% survey respondents considered maternal immunization as part of their role, and only 47% were aware of the national recommendation. Consequently, the uptake of maternal vaccination in KSA may be sub-optimal. The key barriers that hinder obstetricians/gynecologists from recommending maternal Tdap immunization were the anticipation of patient refusal, and their own need for more information/experience about the disease and the national recommendation. Vaccine availability and supply were important barriers, whereas cost/reimbursement and resource issues were of lesser concern. Disseminating evidence based information to physicians, educating pregnant women and addressing public misconceptions.
百白破是一种严重且可能致命的疾病,对于未接种疫苗的婴儿来说尤其危险。尽管儿童疫苗接种率很高,但沙特阿拉伯王国(KSA)仍有未接种疫苗的婴儿发生百日咳。现有数据支持使用母体百日咳免疫接种来预防婴幼儿百日咳。2019 年 6 月,沙特卫生部建议在每次妊娠期间使用破伤风、白喉和无细胞百日咳联合疫苗(Tdap)进行母体百日咳免疫接种。为了了解母体免疫接种的障碍并确定改善母体免疫接种的策略,我们于 2020 年 11 月至 12 月进行了一项在线调查,询问 60 名妇产科医生对母体百日咳免疫接种的态度。不到 50%的调查受访者认为母体免疫接种是其职责的一部分,只有 47%的人了解国家建议。因此,沙特阿拉伯的母体疫苗接种率可能不理想。阻碍妇产科医生推荐母体 Tdap 免疫接种的主要障碍是患者拒绝的预期,以及他们自己对疾病和国家建议的更多信息/经验的需求。疫苗的可及性和供应是重要的障碍,而成本/报销和资源问题则不太重要。向医生传播基于证据的信息、教育孕妇和解决公众的误解。