VBNC 状态：的基本生存策略。
The VBNC state: a fundamental survival strategy of .
机构信息
Department of Molecular Microbiology & Bioenergetics, Institute of Molecular Biosciences, Goethe-University , Frankfurt am Main, Germany.
Institute for Medical Virology, University Hospital Frankfurt, Goethe University , Frankfurt am Main, Germany.
出版信息
mBio. 2023 Oct 31;14(5):e0213923. doi: 10.1128/mbio.02139-23. Epub 2023 Sep 28.
Currently, the viable but non-culturable (VBNC) state is an underappreciated niche for pathogenic bacteria which provides a continuous source for recurrent infections and transmission. We propose the VBNC state to be a global persistence mechanism used by various strains to cope with many stresses it is confronted with in the clinical environment and in the host. This requires a novel strategy to detect viable cells of this pathogen that is not only based on plating assays.
目前，可生存但非可培养（VBNC）状态是一种被低估的病原体小生境，为反复感染和传播提供了持续的来源。我们提出 VBNC 状态是各种菌株用于应对临床环境和宿主中面临的多种压力的全球持久性机制。这需要一种新的策略来检测这种病原体的活细胞，而不仅仅是基于平板检测。
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