From the Department of Nuclear Medicine and PET/CT, King Hussein Cancer Center.
Clin Nucl Med. 2023 Nov 1;48(11):965-966. doi: 10.1097/RLU.0000000000004802. Epub 2023 Sep 21.
68 Ga-FAPI has been introduced recently in many nuclear medicine centers. Many pitfalls have been discussed previously. However, not all pitfalls are currently addressed in the literature. To our knowledge, this is the first reported case to address nonspecific 68 Ga-FAPI expression at anorectal sphincter. A 69-year-old woman was diagnosed with intrahepatic cholangiocarcinoma. A 68 Ga-FAPI scan was performed after diagnostic workup and chemoradiotherapy. In addition to 68 Ga-FAPI-avid lesion at primary site, several nononcological ancillary findings have been observed. This includes unaddressed 68 Ga-FAPI-avid focus within anorectal sphincter. Moreover, the same noteworthy findings were observed in the musculoskeletal and gynecological systems.
68Ga-FAPI 最近在许多核医学中心得到了应用。之前已经讨论了许多陷阱。然而,并非所有陷阱在文献中都有涉及。据我们所知,这是首例报道的肛门直肠括约肌出现非特异性 68Ga-FAPI 表达的病例。一名 69 岁女性被诊断为肝内胆管细胞癌。在进行诊断性检查和放化疗后,进行了 68Ga-FAPI 扫描。除了原发性部位的 68Ga-FAPI 阳性病变外,还观察到了几个非肿瘤性的辅助发现。这包括未解决的肛门直肠括约肌内的 68Ga-FAPI 阳性病灶。此外,在肌肉骨骼和妇科系统中也观察到了同样值得注意的发现。